Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 5/20 | 0.52 |
| ▸ | PPARG | P37231 | 4/20 | 0.52 |
| ▸ | KLK7 | P49862 | 3/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.51 |
| ▸ | NPY2R | P49146 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089459 | 0.83 | KLK7 (0.52) | ALDH1A1KLK7MEN1KMT2AHDAC2 | |
| SCHEMBL4993002 | 0.80 | PPARA (0.69) | PPARAPPARGPPARD | |
| SCHEMBL1670312 | 0.80 | PPARA (0.69) | PPARAPPARGPPARD | |
| SCHEMBL30688252 | 0.80 | PPARG (0.54) | PPARAPPARGKLK7MEN1KMT2A | |
| SCHEMBL29006056 | 0.79 | KLK7 (0.52) | ALDH1A1TP53KLK7NPY1RNPY2R | |
| SCHEMBL15246753 | 0.79 | PPARA (0.56) | PPARAPPARGPPARD | |
| SCHEMBL11642274 | 0.78 | HDAC2 (0.62) | ALDH1A1MEN1KMT2AHDAC2 | |
| SCHEMBL23933829 | 0.78 | SRR (0.46) | PPARAPPARGPPARDMMP8 | |
| SCHEMBL23933826 | 0.78 | SRR (0.46) | PPARAPPARGPPARDMMP8 | |
| SCHEMBL23933832 | 0.78 | SRR (0.46) | PPARAPPARGPPARDMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814866-A2 | GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006058012-A2 | GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS | WYETH (US) | 2006-06-01 | — | — | WO | disclosed |