Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL243317 | 0.83 | CYP2C19 (0.37) | CNR2ALDH1A1KMT2ACYP2C19MEN1 | |
| SCHEMBL4614224 | 0.81 | ALDH1A1 (0.43) | CNR2ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL9551526 | 0.81 | CYP2C19 (0.36) | CNR2ALDH1A1KMT2ACYP2C19MEN1 | |
| SCHEMBL9446177 | 0.81 | CNR2 (0.35) | CNR2ALDH1A1KMT2ACYP2C19MEN1 | |
| SCHEMBL244699 | 0.79 | MAPT (0.37) | CNR2ALDH1A1KMT2ACYP2C19MEN1 | |
| SCHEMBL19212269 | 0.78 | CYP3A4 (0.39) | CNR2ALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL5529306 | 0.78 | MAPT (0.36) | CNR2ALDH1A1KMT2AL3MBTL1TDP1 | |
| SCHEMBL29387582 | 0.78 | CYP1A2 (0.51) | CNR2ALDH1A1KMT2ACYP2C19MEN1 | |
| SCHEMBL5526466 | 0.78 | MAPT (0.36) | CNR2ALDH1A1KMT2AL3MBTL1TDP1 | |
| SCHEMBL1145069 | 0.78 | GPR84 (0.43) | CNR2TRPV1CYP3A4SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828111-A2 | METHODS AND FLUORINATED COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | Neurochem (International) Limited (CH) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006059252-A2 | METHODS AND FLUORINATED COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2006-06-08 | — | — | WO | disclosed |