Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | DDR1 | Q08345 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5517336 | 1.00 | P2RX7 (0.43) | P2RX7DDR1LMNARIPK1F2 | |
| SCHEMBL582729 | 1.00 | P2RX7 (0.43) | P2RX7DDR1LMNARIPK1F2 | |
| SCHEMBL5513992 | 0.88 | KMT2A (0.46) | DDR1LMNARIPK1CETPTP53 | |
| SCHEMBL582826 | 0.88 | KMT2A (0.46) | DDR1LMNARIPK1CETPTP53 | |
| SCHEMBL5517353 | 0.88 | KMT2A (0.46) | DDR1LMNARIPK1CETPTP53 | |
| SCHEMBL5524961 | 0.86 | AKR1B1 (0.42) | P2RX7DDR1LMNARIPK1CETP | |
| SCHEMBL582897 | 0.86 | AKR1B1 (0.42) | P2RX7DDR1LMNARIPK1CETP | |
| SCHEMBL5511603 | 0.86 | AKR1B1 (0.42) | P2RX7DDR1LMNARIPK1CETP | |
| SCHEMBL582810 | 0.84 | RIPK1 (0.44) | LMNARIPK1CETPTP53SUCNR1 | |
| SCHEMBL5519482 | 0.84 | RIPK1 (0.44) | LMNARIPK1CETPTP53SUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7268153-B2 | N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators | MERCK & CO., INC. (US) | 2007-09-11 | — | — | US | claimed |