Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 9/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21518405 | 0.70 | KMT2A (0.39) | EPHX2LMNAHTTEPHX1KMT2A | |
| SCHEMBL30142406 | 0.69 | KMT2A (0.41) | EPHX2KMT2ASMN1; SMN2ALDH1A1CA12 | |
| SCHEMBL5079705 | 0.67 | GRIN2D (0.43) | EPHX2LMNAHTTEPHX1KMT2A | |
| SCHEMBL5079704 | 0.67 | GRIN2D (0.43) | EPHX2LMNAHTTEPHX1KMT2A | |
| SCHEMBL105165 | 0.67 | GRIN2D (0.52) | EPHX2LMNAHTTEPHX1KMT2A | |
| SCHEMBL13464443 | 0.67 | EPHX2 (0.36) | EPHX2LMNAEPHX1KMT2ASMN1; SMN2 | |
| Sulfuric Acid SCHEMBL15211032 | 0.66 | GRIN2D (0.73) | EPHX2LMNAEPHX1KMT2ASMN1; SMN2 | |
| SCHEMBL8812116 | 0.66 | SMN1; SMN2 (0.53) | EPHX2LMNAHTTEPHX1KMT2A | |
| SCHEMBL839162 | 0.66 | SMN1; SMN2 (0.53) | EPHX2LMNAHTTEPHX1KMT2A | |
| SCHEMBL839161 | 0.66 | SMN1; SMN2 (0.53) | EPHX2LMNAHTTEPHX1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828111-A2 | METHODS AND FLUORINATED COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | Neurochem (International) Limited (CH) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006059252-A2 | METHODS AND FLUORINATED COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2006-06-08 | — | — | WO | disclosed |