Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 11/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21518405 | 0.72 | KMT2A (0.39) | KMT2ASMN1; SMN2EPHX2CA12CA2 | |
| SCHEMBL5509409 | 0.69 | EPHX2 (0.37) | KMT2ASMN1; SMN2EPHX2ALDH1A1CA12 | |
| SCHEMBL30189438 | 0.68 | GRIN2D (0.49) | EPHX2 | |
| SCHEMBL354387 | 0.68 | EPHX2 (0.39) | KMT2ASMN1; SMN2EPHX2CA12CA2 | |
| SCHEMBL12226580 | 0.68 | EPHX2 (0.39) | KMT2ASMN1; SMN2EPHX2CA12CA2 | |
| SCHEMBL29391933 | 0.67 | ALDH1A1 (0.40) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL17923279 | 0.67 | SMN1; SMN2 (0.44) | KMT2ASMN1; SMN2EPHX2ALDH1A1CA12 | |
| SCHEMBL5154817 | 0.67 | HDAC7 (0.43) | CA12CA2CA7CA14 | |
| SCHEMBL7028930 | 0.67 | HDAC7 (0.38) | CA12CA2CA7CA14 | |
| SCHEMBL21268065 | 0.66 | RAB9A (0.37) | SMN1; SMN2ALDH1A1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4107198-A1 | POLYISOCYANATE PREPARATIONS | Covestro Deutschland AG (DE) | 2022-12-28 | — | — | EP | disclosed |