Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5512480 | 0.88 | CHRM2 (0.43) | SLC6A2SLC6A4SLC6A3CHRM2HTR1A | |
| SCHEMBL5512484 | 0.88 | CHRM2 (0.43) | SLC6A2SLC6A4SLC6A3CHRM2HTR1A | |
| SCHEMBL5520718 | 0.78 | LMNA (0.43) | LMNAALDH1A1 | |
| SCHEMBL6170700 | 0.78 | LMNA (0.43) | LMNAALDH1A1 | |
| SCHEMBL692543 | 0.78 | KLK7 (0.44) | CHRM1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL5510848 | 0.77 | FPR2 (0.39) | SLC6A2SLC6A4SLC6A3LMNANPSR1 | |
| SCHEMBL5516590 | 0.77 | PPARG (0.48) | LMNAALDH1A1CNR1MEN1KMT2A | |
| SCHEMBL5516586 | 0.77 | PPARG (0.48) | LMNAALDH1A1CNR1MEN1KMT2A | |
| SCHEMBL6168522 | 0.77 | PPARG (0.48) | LMNAALDH1A1CNR1MEN1KMT2A | |
| SCHEMBL5510728 | 0.76 | IDO1 (0.48) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279478-B2 | Cathepsin cysteine protease inhibitors | MERCK FROSST CANADA & CO. (CA) | 2007-10-09 | — | — | US | disclosed |