Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PREP | P48147 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.33 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.33 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25370505 | 0.86 | CA12 (0.41) | CA12CA1CA9ALDH1A1PREP | |
| SCHEMBL4753702 | 0.81 | CA12 (0.46) | CA12CA1CA9ALDH1A1PREP | |
| SCHEMBL1885083 | 0.80 | CA12 (0.46) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL7308992 | 0.78 | CA12 (0.43) | CA12CA1CA9ALDH1A1PREP | |
| SCHEMBL1604135 | 0.78 | CA12 (0.43) | CA12CA1CA9ALDH1A1PREP | |
| SCHEMBL29053391 | 0.78 | CA12 (0.46) | CA12CA1CA9ALDH1A1PREP | |
| SCHEMBL30629166 | 0.78 | SMN1; SMN2 (0.39) | CA12CA1CA9ALDH1A1PREP | |
| SCHEMBL28613347 | 0.77 | CA12 (0.43) | CA12CA1CA9ALDH1A1PREP | |
| SCHEMBL6211617 | 0.77 | KDM4E (0.47) | CA12CA1CA9ALDH1A1PREP | |
| SCHEMBL9097136 | 0.77 | CA12 (0.44) | CA12CA1CA9ALDH1A1PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848463-A2 | METHOD OF CONJUGATING AMINOTHIOL CONTAINING MOLECULES TO VEHICLES | Amgen Inc. (US) | 2007-10-31 | — | — | EP | disclosed |
| US-20060199812-A1 | Method of conjugating aminothiol containing molecules to vehicles | AMGEN INC. | 2006-09-07 | — | — | US | disclosed |
| WO-2006079099-A2 | METHOD OF CONJUGATING AMINOTHIOL CONTAINING MOLECULES TO A POLYMER | AMGEN INC. (US) | 2006-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199812-A1 | Method of conjugating aminothiol containing molecules to vehicles | SLC7A1, QPCT, SLC7A5 | CA12 1890/4885CA1 2857/4885CA9 3333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.