Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1863306 | 0.90 | REN (0.55) | RENCYP3A4 | |
| SCHEMBL1863304 | 0.90 | REN (0.55) | RENCYP3A4 | |
| SCHEMBL5593562 | 0.86 | REN (0.48) | RENCYP3A4 | |
| SCHEMBL8269143 | 0.86 | REN (0.54) | RENCYP3A4 | |
| SCHEMBL4754618 | 0.84 | REN (0.69) | RENCYP3A4 | |
| SCHEMBL1865140 | 0.84 | REN (0.69) | REN | |
| SCHEMBL1862835 | 0.84 | REN (0.69) | REN | |
| SCHEMBL1861751 | 0.84 | REN (0.69) | REN | |
| SCHEMBL1865775 | 0.84 | REN (0.69) | REN | |
| SCHEMBL1865778 | 0.84 | REN (0.69) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007117560-A2 | PIPERIDINE AND MORPHOLINE RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-10-18 | — | — | WO | disclosed |
| EP-1807078-A1 | DIAMINOALKANE ASPARTIC PROTEASE INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006042150-A1 | DIAMINOALKANE ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2006-04-20 | — | — | WO | disclosed |