Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL23R | Q5VWK5 | 11/20 | 0.59 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.56 |
| ▸ | PTH1R | Q03431 | 3/20 | 0.55 |
| ▸ | GLP1R | P43220 | 2/20 | 0.55 |
| ▸ | ECE1 | P42892 | 1/20 | 0.55 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5509790 | 1.00 | IL23R (0.59) | IL23RPRMT1PTH1RGLP1RECE1 | |
| SCHEMBL29895786 | 0.89 | IL23R (0.52) | IL23RPRMT1 | |
| SCHEMBL29725771 | 0.88 | GRPR (0.59) | IL23RPTH1RRXFP1 | |
| SCHEMBL31504096 | 0.88 | GRPR (0.59) | IL23RPTH1RRXFP1 | |
| SCHEMBL29434537 | 0.88 | GLP1R (0.57) | IL23RGLP1R | |
| SCHEMBL29963494 | 0.87 | CCKBR (0.55) | IL23RPRMT1PTH1RGLP1RECE1 | |
| SCHEMBL30262192 | 0.87 | GLP1R (0.67) | IL23RPTH1RGLP1RECE1MUS81 | |
| SCHEMBL30405497 | 0.87 | GRPR (0.58) | IL23RPTH1RRXFP1 | |
| SCHEMBL30512502 | 0.86 | PTH1R (0.63) | IL23RPTH1RGLP1RECE1MUS81 | |
| SCHEMBL29939662 | 0.86 | PRMT1 (0.64) | IL23RPRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217571-B1 | Gene therapy by small fragment homologous replacement | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-05-15 | — | — | US | disclosed |
| EP-0636028-B1 | SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM COMPRISING AN AMPHIPHATIC CATIONIC PEPTIDE | UNIV CALIFORNIA (US) | 2004-03-03 | — | — | EP | disclosed |
| EP-0708637-B1 | SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM COMPRISING DENDRIMER POLYCATIONS | UNIV CALIFORNIA (US) | 2004-01-28 | — | — | EP | disclosed |
| EP-1236473-A2 | Self-assembling polynucleotide delivery system | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-09-04 | — | — | EP | disclosed |
| US-6113946-A | EUKARYOTIC CELL, POLYNUCLEOTIDE AND DENDRIMER POLYCATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-09-05 | — | — | US | disclosed |
| US-6010908-A | IN SITU REPLACEMENT OF AN EXON CARRYING AN ENDOGENOUS TARGETED MUTANT DNA SEQUENCE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-01-04 | — | — | US | disclosed |
| US-5990089-A | INTRODUCING A POLYNUCLEOTIDE INTO A EUKARYOTIC CELL IN A LIVING ANIMAL COMPRISING CONTACTING THE CELL WITH A COMPOSITION COMPRISING A POLYNUCLEOTIDE AND A DENDRIMER POLYCATION COUPLED TO THE POLYNUCLEOTIDE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-11-23 | — | — | US | disclosed |
| EP-0708637-A4 | SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM COMPRISING DENDRIMER POLYCATIONS | UNIV CALIFORNIA (US) | 1998-08-12 | — | — | EP | disclosed |
| CN-1178797-A | Oligopeptide derivative containing alpha, gamma-diaminobutanoic acid | HOFFMANN LA ROCHE (CH) | 1998-04-15 | — | — | CN | disclosed |
| EP-0834572-A2 | Alpha, gamma-diaminobutyric acid (DAB) containing oligopeptide derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1998-04-08 | — | — | EP | disclosed |
| EP-0656747-A4 | COMPOSITION AND METHOD FOR ALTERING DNA SEQUENCES BY HOMOLOGOUS RECOMBINATION. | UNIV CALIFORNIA (US) | 1997-05-07 | — | — | EP | disclosed |
| EP-0708637-A1 | SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM COMPRISING DENDRIMER POLYCATIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-05-01 | — | — | EP | disclosed |
| EP-0656747-A1 | COMPOSITION AND METHOD FOR ALTERING DNA SEQUENCES BY HOMOLOGOUS RECOMBINATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-06-14 | — | — | EP | disclosed |
| WO-1995002397-A1 | SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM COMPRISING DENDRIMER POLYCATIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-01-26 | — | — | WO | disclosed |
| WO-1994004032-A1 | COMPOSITION AND METHOD FOR ALTERING DNA SEQUENCES BY HOMOLOGOUS RECOMBINATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-03-03 | — | — | WO | disclosed |