⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27624459 | 0.97 | TSHR (0.31) | — | |
| SCHEMBL3611613 | 0.84 | SOS1 (0.31) | — | |
| SCHEMBL4002326 | 0.82 | SIGMAR1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL1930007 | 0.80 | SIGMAR1 (0.31) | — | |
| SCHEMBL29788762 | 0.78 | SIGMAR1 (0.31) | — | |
| SCHEMBL25260331 | 0.76 | — | — | |
| SCHEMBL13161904 | 0.70 | — | — | |
| SCHEMBL12286669 | 0.69 | — | — | |
| SCHEMBL24847108 | 0.69 | DRD2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL18306053 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4562018-A1 | COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | Biogen MA Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| CN-119948036-A | Compounds for the treatment of huntington's disease | 渤健马萨诸塞州股份有限公司 | 2025-05-06 | — | — | CN | disclosed |
| WO-2024026061-A1 | COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | BIOGEN MA INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| CN-116157392-A | Compounds targeting RNA binding proteins or RNA modification proteins | 雷多纳治疗公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-111943946-B | Dihydroquinazinone carboxylic acid compound containing nitrogen heterocyclic segment and application thereof | 中国医学科学院医药生物技术研究所 | 2022-07-01 | — | — | CN | disclosed |
| CN-111943946-A | Dihydroquinazinone carboxylic acid compound containing nitrogen heterocyclic segment and application thereof | 中国医学科学院医药生物技术研究所 | 2020-11-17 | — | — | CN | disclosed |
| CN-103819459-B | Anti-Viral Compounds | 艾伯维巴哈马有限公司 | 2017-05-17 | — | — | CN | disclosed |
| WO-2014124560-A1 | MGLUR REGULATORS | HUA MEDICINE (SHANGHAI) LTD. (CN) | 2014-08-21 | — | — | WO | disclosed |
| CN-102333772-A | Antiviral compounds | ABBOTT LAB | 2012-01-25 | — | — | CN | disclosed |
| CN-101289445-A | Aniline quinazoline derivatives, preparation method and uses thereof | SHANGHAI INST MATERIA MEDICA (CN) | 2008-10-22 | — | — | CN | disclosed |
| CN-101087778-A | Pyrrolidinyl derivatives of heteroaromatic compounds as phosphodiesterase inhibitors | PFIZER (US) | 2007-12-12 | — | — | CN | disclosed |
| EP-1838702-A1 | PYRROLIDYL DERIVATIVES OF HETEROAROMATIC COMPOUNDS AS PHOSPHODIESTERASE INHIBITORS | Pfizer Products Inc. (US) | 2007-10-03 | — | — | EP | disclosed |
| US-20060183763-A1 | Novel pyrrolidyl derivatives of heteroaromatic compounds | PFIZER INC | 2006-08-17 | — | — | US | disclosed |
| WO-2006070284-A1 | PYRROLIDYL DERIVATIVES OF HETEROAROMATIC COMPOUNDS AS PHOSPHODIESTERASE INHIBITORS | PFIZER PRODUCTS INC. (US) | 2006-07-06 | — | — | WO | disclosed |
| WO-2006070284-A1 | PYRROLIDYL DERIVATIVES OF HETEROAROMATIC COMPOUNDS AS PHOSPHODIESTERASE INHIBITORS | PFIZER PRODUCTS INC. (US) | 2006-07-06 | — | — | WO | disclosed |
| EP-0562042-A4 | QUINOLINE, NAPHTHYRIDINE AND PYRIDOBENZOXAZINE DERIVATIVES | ABBOTT LAB (US) | 1994-07-06 | — | — | EP | disclosed |
| EP-0562042-A1 | QUINOLINE, NAPHTHYRIDINE AND PYRIDOBENZOXAZINE DERIVATIVES | ABBOTT LABORATORIES (US) | 1993-09-29 | — | — | EP | disclosed |
| US-5137892-A | Bactericides | ABBOTT LABORATORIES (US) | 1992-08-11 | — | — | US | disclosed |
| WO-1992010191-A1 | QUINOLINE, NAPHTHYRIDINE AND PYRIDOBENZOXAZINE DERIVATIVES | ABBOTT LABORATORIES (US) | 1992-06-25 | — | — | WO | disclosed |