Sulfuric Acid

Sulfuric Acid

SCHEMBL5509950

NC(CSCCNC(=O)OCc1ccccc1)C(=O)O.O=S(=O)(O)O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.58
SLC1A1 P43005 1/20 0.58
LMNA P02545 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
DPP8 Q6V1X1 2/20 0.48
DPP7 Q9UHL4 2/20 0.48
HTT P42858 1/20 0.48
MMP2 P08253 3/20 0.47
MMP9 P14780 3/20 0.47
ANPEP P15144 1/20 0.47
TGM2 P21980 1/20 0.46
CA1 P00915 3/20 0.46
CA2 P00918 3/20 0.46
CA12 O43570 2/20 0.46
CA9 Q16790 2/20 0.46
DPP4 P27487 1/20 0.45
DPP9 Q86TI2 1/20 0.45
FOLH1 Q04609 2/20 0.45
KEAP1 Q14145 1/20 0.45
NFE2L2 Q16236 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL5509948 1.00 SLC1A3 (0.58) SLC1A3SLC1A1LMNASMN1; SMN2DPP8
SCHEMBL10825360 0.95 SLC1A3 (0.62) SLC1A3SLC1A1LMNASMN1; SMN2DPP8
SCHEMBL15372902 0.95 SLC1A3 (0.62) SLC1A3SLC1A1LMNASMN1; SMN2DPP8
SCHEMBL7422583 0.88 SLC1A3 (0.60) SLC1A3SLC1A1LMNASMN1; SMN2DPP8
SCHEMBL7422580 0.88 SLC1A3 (0.60) SLC1A3SLC1A1LMNASMN1; SMN2DPP8
SCHEMBL1429727 0.88 SLC1A3 (0.56) SLC1A3SLC1A1LMNASMN1; SMN2DPP8
SCHEMBL10825548 0.84 SLC1A3 (0.65) SLC1A3SLC1A1LMNASMN1; SMN2DPP8
SCHEMBL10825552 0.84 SLC1A3 (0.65) SLC1A3SLC1A1LMNASMN1; SMN2DPP8
SCHEMBL11714774 0.83 SLC1A1 (0.58) SLC1A3SLC1A1LMNASMN1; SMN2DPP8
Hydrochloric Acid SCHEMBL11716861 0.82 SLC1A1 (0.57) SLC1A3SLC1A1LMNASMN1; SMN2DPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE39576-E1 Enzyme inhibitors SMITHKLINE BEECHAM CORPORATION (US) 2007-04-17 US disclosed
EP-0957087-B1 Intermediates useful in the preparation of enzyme inhibitors WELLCOME FOUND (GB) 2002-12-04 EP disclosed
EP-0765308-B1 ENZYME INHIBITORS WELLCOME FOUND (GB) 2000-04-05 EP disclosed
EP-0957087-A2 Enzyme inhibitors THE WELLCOME FOUNDATION LIMITED (GB) 1999-11-17 EP disclosed
US-5889056-A OF NITRIC OXIDE SYNTHASE; HYPOTENSIVE AGENT, ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS GLAXO WELLSOME INC. (US) 1999-03-30 US disclosed
EP-0765308-A1 ENZYME INHIBITORS THE WELLCOME FOUNDATION LIMITED (GB) 1997-04-02 EP disclosed
WO-1995034534-A1 ENZYME INHIBITORS THE WELLCOME FOUNDATION LIMITED (GB) 1995-12-21 WO disclosed