Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.71 |
| ▸ | JAK2 | O60674 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GPX4 | P36969 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | ICMT | O60725 | 1/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469093 | 1.00 | NPC1 (0.71) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL7995028 | 1.00 | NPC1 (0.71) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL8032558 | 1.00 | NPC1 (0.71) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL894066 | 0.98 | NPC1 (0.69) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL2892022 | 0.93 | NPC1 (0.61) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL17473048 | 0.91 | NPC1 (0.57) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL30957362 | 0.91 | NPC1 (0.57) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL10961189 | 0.89 | NPC1 (0.71) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL10963783 | 0.89 | NPC1 (0.71) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL10960608 | 0.89 | NPC1 (0.71) | NPC1RAB9APAX8JAK2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470258-B1 | COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS | TFL LEDERTECHNIK GMBH (DE) | 2013-08-28 | — | — | EP | disclosed |
| US-7250456-B2 | Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials | TFL LEDERTECHNIK GMBH (DE) | 2007-07-31 | — | — | US | disclosed |
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| US-20050148702-A1 | Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials | TFL LEDERTECHNIK GMBH (DE) | 2005-07-07 | — | — | US | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |
| EP-1470258-A1 | COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS | TFL Ledertechnik GmbH (DE) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064707-A1 | COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS | TFL LEDERTECHNIK GMBH (DE) | 2003-08-07 | — | — | WO | disclosed |
| EP-0752413-B1 | Process for the production of aromatic carbamates | MINI RICERCA SCIENT TECNOLOG (IT) | 1999-04-28 | — | — | EP | disclosed |
| US-5698731-A | REACTING ALKYL CARBONATE AND AROMATIC AMINES IN PRESENCE OF CARBAMATION CATALYST SELECTED FROM N,N-DISUBSTITUTED CARBAMATE COMPLEXS OF ZINC OR COPPER | Ministero Dell `Universita` e Della Ricerca Scientifica e Tecnologica (IT) | 1997-12-16 | — | — | US | disclosed |
| EP-0752413-A1 | Process for the production of aromatic carbamates | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1997-01-08 | — | — | EP | disclosed |