Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.71 |
| ▸ | JAK2 | O60674 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GPX4 | P36969 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | ICMT | O60725 | 1/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469093 | 1.00 | NPC1 (0.71) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL5509984 | 1.00 | NPC1 (0.71) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL8032558 | 1.00 | NPC1 (0.71) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL894066 | 0.98 | NPC1 (0.69) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL2892022 | 0.93 | NPC1 (0.61) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL17473048 | 0.91 | NPC1 (0.57) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL30957362 | 0.91 | NPC1 (0.57) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL10961189 | 0.89 | NPC1 (0.71) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL10963783 | 0.89 | NPC1 (0.71) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL10960608 | 0.89 | NPC1 (0.71) | NPC1RAB9APAX8JAK2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294502-B1 | Thermally-responsive record material | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-25 | — | — | US | claimed |
| WO-1999061251-A1 | THERMALLY-RESPONSIVE RECORD MATERIAL CONTAINING A CARBAMATE COMPONENT | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-02 | — | — | WO | claimed |
| US-6294502-B1 | Thermally-responsive record material | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-25 | — | — | US | disclosed |
| US-6294502-B1 | Thermally-responsive record material | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-25 | — | — | US | disclosed |
| WO-1999061251-A1 | THERMALLY-RESPONSIVE RECORD MATERIAL CONTAINING A CARBAMATE COMPONENT | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-02 | — | — | WO | disclosed |
| WO-1999061251-A1 | THERMALLY-RESPONSIVE RECORD MATERIAL CONTAINING A CARBAMATE COMPONENT | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-02 | — | — | WO | disclosed |