Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1115865 | 0.81 | CYP1A2 (0.46) | CYSLTR1CYSLTR2CYP1A2PDE10ANCF1 | |
| SCHEMBL456812 | 0.81 | CYP1A2 (0.46) | CYSLTR1CYSLTR2CYP1A2PDE10ANCF1 | |
| SCHEMBL8754671 | 0.81 | CYSLTR1 (0.46) | CYSLTR1CYSLTR2CYP1A2PDE10ANCF1 | |
| SCHEMBL8754663 | 0.81 | CYSLTR1 (0.46) | CYSLTR1CYSLTR2CYP1A2PDE10ANCF1 | |
| SCHEMBL5093242 | 0.81 | CYP1A2 (0.46) | CYSLTR1CYSLTR2CYP1A2PDE10ANCF1 | |
| SCHEMBL6535913 | 0.81 | CYSLTR1 (0.46) | CYSLTR1CYSLTR2CYP1A2PDE10ANCF1 | |
| SCHEMBL322184 | 0.81 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2CYP1A2PDE10ANCF1 | |
| SCHEMBL1163878 | 0.81 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2CYP1A2PDE10ANCF1 | |
| SCHEMBL6525088 | 0.80 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2CYP1A2PDE10ANCF1 | |
| SCHEMBL17500352 | 0.80 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2CYP1A2PDE10AGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39836-E1 | Macrolide antinfective agents | KOSAN BIOSCIENCES, INC. (US) | 2007-09-11 | — | — | US | claimed |
| US-6593302-B2 | Antibiotics | KOSAN BIOSCIENCES, INC. | 2003-07-15 | — | — | US | claimed |