SCHEMBL322184

SCHEMBL322184

C=CCc1ccc2ccccc2n1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYSLTR1 Q9Y271 2/20 0.49
CYSLTR2 Q9NS75 1/20 0.49
CYP1A2 P05177 2/20 0.45
NCF1 P14598 1/20 0.42
NOS2 P35228 1/20 0.42
BACE1 P56817 1/20 0.42
CA12 O43570 1/20 0.42
CA9 Q16790 1/20 0.42
PDE10A Q9Y233 2/20 0.41
GPBAR1 Q8TDU6 1/20 0.40
LMNA P02545 1/20 0.40
KDM1A O60341 1/20 0.40
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL28854191 0.98 CYSLTR1 (0.47) CYSLTR1CYSLTR2CYP1A2NCF1NOS2
Quinoline SCHEMBL11076491 0.90 ALDH1A1 (0.55) CYSLTR1CYSLTR2CYP1A2PDE10AGPBAR1
SCHEMBL6525088 0.83 CYSLTR1 (0.52) CYSLTR1CYSLTR2CYP1A2NCF1NOS2
SCHEMBL17227498 0.82 CYSLTR1 (0.50) CYSLTR1CYSLTR2CYP1A2NCF1NOS2
SCHEMBL5510083 0.81 CYSLTR1 (0.46) CYSLTR1CYSLTR2CYP1A2NCF1NOS2
SCHEMBL4128709 0.81 PDE10A (0.46) CYSLTR1CYSLTR2CYP1A2PDE10A
SCHEMBL1777676 0.80 CYSLTR1 (0.49) CYSLTR1CYSLTR2CYP1A2NCF1NOS2
SCHEMBL9287417 0.80 CYP1A2 (0.49) CYSLTR1CYSLTR2CYP1A2NCF1NOS2
SCHEMBL5238162 0.80 CYP1A2 (0.49) CYSLTR1CYSLTR2CYP1A2NCF1NOS2
SCHEMBL1163878 0.80 CYSLTR1 (0.49) CYSLTR1CYSLTR2CYP1A2NCF1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 809 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120041180-A Complex water quality flowback fluid direct-matching functional fracturing fluid 成都劳恩普斯科技有限公司 2025-05-27 CN claimed
CN-116715628-A Synthesis method of quinoline-substituted homoallylamine compound 中国科学技术大学 2023-09-08 CN claimed
EP-3377104-B1 MODULATING PERMEABILITY OF THE BLOOD CEREBROSPINAL FLUID BARRIER MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2022-12-21 EP claimed
CN-115044215-A Nano modified asphalt and preparation method thereof 王秀庆 2022-09-13 CN claimed
CN-108472370-B Modulating blood cerebrospinal fluid barrier permeability 纪念斯隆-凯特琳癌症中心 2022-07-12 CN claimed
CN-110240715-B Method for quickly dissolving gelatin in Bronsted acidic ionic liquid at low temperature 南京工业大学 2022-02-15 CN claimed
EP-3138890-B1 AGGREGATING COMPOSITIONS, MODIFIED PARTICULATE METAL OXIDES, MODIFIED FORMATION SURFACES, AND METHODS FOR MAKING AND USING SAME LUBRIZOL CORP (US) 2020-11-11 EP claimed
EP-3071666-B1 METHOD AND COMPOSITION FOR CONSOLIDATING SOLID MATERIALS DURING SUBTERRANEAN TREATMENT OPERATIONS LUBRIZOL CORP (US) 2020-08-12 EP claimed
CN-110372725-A A kind of polycyclic polysubstituted tetrahydroquinoline of bridged ring and preparation method thereof 河南大学 2019-10-25 CN claimed
CN-105745300-B Method of consolidating solid materials during subterranean treatment operations 韦特福特科技控股有限责任公司 2019-10-22 CN claimed
WO-1999062072-A1 A METHOD FOR REMOVING INORGANIC MATTER FROM SOLID SURFACES BRITISH NUCLEAR FUELS PLC (GB) 1999-12-02 WO claimed
EP-0905214-A2 Desulphurization method for catalytically cracked gasoline Mitsubishi Oil Co., Ltd. (JP) 1999-03-31 EP claimed
US-5779938-A A REACTION PRODUCT OF AN ALKYL TERTIARY AMINE OF AN ALKYL DERIVATIVE OF PYRIDINE OR QUINOLINE; CONTINUOUS INJECTION IN PIPELINES CARRYING OIL OR GAS; PROTECTION OF IRON OR IRON ALLOY SURFACES CHAMPION TECHNOLOGIES, INC. (US) 1998-07-14 US claimed
WO-1997008264-A1 COMPOSITIONS AND METHODS FOR INHIBITING CORROSION CHAMPION TECHNOLOGIES, INC. (US) 1997-03-06 WO claimed
EP-0521738-B1 Bath and method for the electroless plating of tin and tin-lead alloy UYEMURA C & CO LTD (JP) 1996-11-06 EP claimed
US-5266103-A Printed circuits C. UYEMURA & CO., LTD. (JP) 1993-11-30 US claimed
EP-0521738-A2 Bath and method for the electroless plating of tin and tin-lead alloy C. UYEMURA & CO, LTD (JP) 1993-01-07 EP claimed
US-5103035-A Process for preparing bis(alkylphenyl)pentaerythritol diphosphites ETHYL CORPORATION (US) 1992-04-07 US claimed
US-4040970-A WITH COPOLYMER FOR RENDERING THE TONER NEGATIVELY CHARGEABLE CANON KABUSHIKI KAISHA (JA) 1977-08-09 US claimed
US-3977983-A Liquid developer for use in development of an electrostatic latent image comprising a copolymer containing an amino group converted into a quaternary ammonium salt or hydroxide CANON KABUSHIKI KAISHA (JA) 1976-08-31 US claimed