Fluoride

Fluoride

SCHEMBL5510554

Clc1ccc(I)cc1.F.F.F.F.F.F.[As]

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.53
CYP2A6 P11509 1/20 0.53
APP P05067 1/20 0.48
IDO1 P14902 2/20 0.40
TSHR P16473 5/20 0.37
CYP1A2 P05177 1/20 0.36
MAPK13 O15264 1/20 0.36
GCGR P47871 1/20 0.36
MAPK12 P53778 1/20 0.36
MAPK11 Q15759 1/20 0.36
MAPK14 Q16539 1/20 0.36
MGLL Q99685 1/20 0.35
MAPK1 P28482 4/20 0.35
CYP3A4 P08684 2/20 0.35
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
ENPP2 Q13822 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HSD17B10 Q99714 1/20 0.35
HIF1A Q16665 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL208292 0.93
Phosphine SCHEMBL10485954 0.90
Iodide SCHEMBL28874739 0.90
Hydrochloric Acid SCHEMBL11778652 0.90 LMNA (0.57) LMNACYP2A6APPIDO1TSHR
SCHEMBL1936967 0.90
Hydrochloric Acid SCHEMBL11778645 0.90 LMNA (0.57) LMNACYP2A6APPIDO1TSHR
SCHEMBL23922757 0.84 CYP1A2 (0.55) LMNACYP2A6APPIDO1TSHR
SCHEMBL4148462 0.84 CYP1A2 (0.55) LMNACYP2A6APPIDO1TSHR
Cyanide SCHEMBL27743900 0.84 LMNA (0.50) LMNACYP2A6APPIDO1TSHR
SCHEMBL4177324 0.81 LMNA (0.47) LMNACYP2A6APPIDO1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1791824-A1 RADICALLY POLYMERIZABLE SULFUR-CONTAINING COMPOUND AND RADICALLY POLYMERIZABLE SULFUR-CONTAINING POLYMER Showa Denko K.K. (JP) 2007-06-06 EP disclosed
WO-2006033438-A1 RADICALLY POLYMERIZABLE SULFUR-CONTAINING COMPOUND AND RADICALLY POLYMERIZABLE SULFUR-CONTAINING POLYMER SHOWA DENKO K.K. (JP) 2006-03-30 WO disclosed