SCHEMBL4148462

SCHEMBL4148462

Clc1ccc(-c2ccc(I)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.55
LMNA P02545 2/20 0.50
CYP2A6 P11509 1/20 0.50
AHR P35869 2/20 0.48
APP P05067 1/20 0.46
ALOX5 P09917 1/20 0.44
MAPK13 O15264 1/20 0.43
GCGR P47871 1/20 0.43
MAPK12 P53778 1/20 0.43
MAPK11 Q15759 1/20 0.43
MAPK14 Q16539 1/20 0.43
MAOB P27338 1/20 0.41
IDO1 P14902 1/20 0.38
KIF11 P52732 1/20 0.38
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
HSD11B1 P28845 1/20 0.37
TSHR P16473 2/20 0.36
TP53 P04637 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23922757 1.00 CYP1A2 (0.55) CYP1A2LMNACYP2A6AHRAPP
SCHEMBL208292 0.90
Hydrochloric Acid SCHEMBL11778652 0.87 LMNA (0.57) CYP1A2LMNACYP2A6APPMAPK13
Iodide SCHEMBL28874739 0.87
Phosphine SCHEMBL10485954 0.87
SCHEMBL1936967 0.87
Hydrochloric Acid SCHEMBL11778645 0.87 LMNA (0.57) CYP1A2LMNACYP2A6APPMAPK13
Fluoride SCHEMBL5510554 0.84 LMNA (0.53) CYP1A2LMNACYP2A6APPMAPK13
SCHEMBL28215 0.83 CYP1A2 (0.73) CYP1A2LMNACYP2A6AHRALOX5
SCHEMBL3952742 0.83 CYP1A2 (0.73) CYP1A2LMNACYP2A6AHRALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116768753-A Squaraine crystal material with solid multi-emission characteristic and preparation and application thereof 北京化工大学 2023-09-19 CN claimed
CN-115073420-A Preparation method of 2-phenylbenzothiophene derivative 陕西维世诺新材料有限公司 2022-09-20 CN claimed
US-20250194416-A1 ORGANIC COMPOUND, AND ELECTRONIC COMPONENT AND ELECTRONIC APPARATUS USING SAME SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2025-06-12 US disclosed
US-20230301184-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-09-21 US disclosed
US-20230301184-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-09-21 US disclosed
CN-116768753-A Squaraine crystal material with solid multi-emission characteristic and preparation and application thereof 北京化工大学 2023-09-19 CN disclosed
US-20230257387-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-08-17 US disclosed
US-20230257387-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-08-17 US disclosed
US-11718583-B2 Nitrogen-containing compound, electronic component using same and electronic device SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-08-08 US disclosed
US-11718583-B2 Nitrogen-containing compound, electronic component using same and electronic device SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-08-08 US disclosed
US-20230139393-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC COMPONENT USING SAME AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-05-04 US disclosed
US-20120070783-A1 RADIATION-SENSITIVE RESIN COMPOSITION, POLYMER, AND METHOD FOR FORMING RESIST PATTERN JSR CORPORATION (JP) 2012-03-22 US disclosed
US-20110315925-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE CHISSO PETROCHEMICAL CORPORATION (JP) 2011-12-29 US disclosed
US-20100308266-A1 Liquid Crystal Composition and Liquid Crystal Display Device CHISSO CORPORATION (JP) 2010-12-09 US disclosed
US-20090136448-A1 Antiviral 2-Carboxy-Thiophene Compounds CORFIELD JOHN ANDREW 2009-05-28 US disclosed
EP-1971599-A1 ANTIVIRAL 2-CARBOXY-THIOPHENE COMPOUNDS SmithKline Beecham Corporation (US) 2008-09-24 EP disclosed
EP-1835007-A2 Nanofibres from functionalised organic molecules Carl von Ossietzky Universität Oldenburg (DE) 2007-09-19 EP disclosed
WO-2007071434-A1 ANTIVIRAL 2-CARBOXY-THIOPHENE COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 2007-06-28 WO disclosed
US-4950817-A CATALYTIC HALOGENATION OF MONOHALO-BIPHENYL BAYER AKTIENGESELLSCHAFT (DE) 1990-08-21 US disclosed
US-4107329-A Fluorinated compounds as therapeutics IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1978-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110315925-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE NLK, LASP1, UACA CYP1A2 3583/4885LMNA 1122/4885CYP2A6 3900/4885
US-20230139393-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC COMPONENT USING SAME AND ELECTRONIC DEVICE EXOC1, NOS1, EXOSC10 CYP1A2 2892/4885LMNA 3381/4885CYP2A6 4002/4885
US-11718583-B2 Nitrogen-containing compound, electronic component using same and electronic device EXOC1, NOS1, EXOSC10 CYP1A2 2892/4885LMNA 3381/4885CYP2A6 4002/4885
US-20090136448-A1 Antiviral 2-Carboxy-Thiophene Compounds EIF2AK2, HAVCR2, MAVS CYP1A2 335/4885LMNA 4627/4885CYP2A6 325/4885
US-20230301184-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS THEREOF OCIAD1, OCIAD2, OSTC CYP1A2 292/4885LMNA 3136/4885CYP2A6 812/4885
US-20250194416-A1 ORGANIC COMPOUND, AND ELECTRONIC COMPONENT AND ELECTRONIC APPARATUS USING SAME ORC3, OR51E2, OR10J3 CYP1A2 340/4885LMNA 4015/4885CYP2A6 740/4885
US-20230257387-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF OCIAD1, OCIAD2, EPCAM CYP1A2 1076/4885LMNA 1667/4885CYP2A6 831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.