Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 13/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.60 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.60 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.60 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.60 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5516857 | 1.00 | DHODH (0.60) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| SCHEMBL14422942 | 0.88 | DHODH (0.62) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| SCHEMBL5511055 | 0.86 | DHODH (0.54) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| SCHEMBL19417215 | 0.85 | HTT (0.71) | DGAT1HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL14422943 | 0.85 | DHODH (0.59) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| SCHEMBL14452173 | 0.83 | HTT (0.58) | DHODHNR4A2DGAT1HTTMEN1 | |
| SCHEMBL6223427 | 0.78 | DHODH (0.59) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| SCHEMBL5509135 | 0.77 | DHODH (0.62) | DHODHNR4A2MEN1KMT2AALDH1A1 | |
| SCHEMBL13370806 | 0.76 | DHODH (0.54) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| SCHEMBL5515802 | 0.76 | DHODH (0.61) | DHODHNR4A2DGAT1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070224672-A1 | Method of Identifying Inhibitors of DHODH | LEBAN JOHANN | 2007-09-27 | — | — | US | disclosed |
| US-7247736-B2 | Method of identifying inhibitors of DHODH | 4SC AG (DE) | 2007-07-24 | — | — | US | disclosed |
| US-20070027193-A1 | Method of identifying inhibitors of DHODH | 4SC AG (DE) | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027193-A1 | Method of identifying inhibitors of DHODH | DHODH, SQOR, NDUFA5 | DHODH 1/4885NR4A2 2196/4885JMJD7 2100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.