Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1B | O00238 | 3/20 | 0.41 |
| ▸ | BMPR1A | P36894 | 3/20 | 0.41 |
| ▸ | ACVRL1 | P37023 | 3/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5004930 | 0.98 | BMPR1B (0.42) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL3035796 | 0.85 | SRD5A1 (0.39) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL2078451 | 0.80 | BMPR1B (0.44) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL5505340 | 0.80 | CYP19A1 (0.37) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL5501426 | 0.79 | BMPR1B (0.34) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL26750443 | 0.79 | BMPR1B (0.43) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL5001377 | 0.78 | CYP19A1 (0.38) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL25318279 | 0.77 | BMPR1B (0.42) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL21001754 | 0.77 | BMPR1B (0.45) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL31178355 | 0.77 | BMPR1B (0.42) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781642-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006016221-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-16 | — | — | WO | disclosed |