Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.37 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.35 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.32 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5001377 | 0.98 | CYP19A1 (0.38) | CYP19A1ATAD2BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL4997606 | 0.86 | ATAD2 (0.44) | CYP19A1ATAD2BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL4997675 | 0.85 | ATAD2 (0.31) | ATAD2 | |
| SCHEMBL5511206 | 0.80 | BMPR1B (0.41) | ATAD2BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL5004930 | 0.78 | BMPR1B (0.42) | CYP19A1ATAD2BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL5509422 | 0.78 | — | — | |
| SCHEMBL5004922 | 0.77 | MEN1 (0.34) | CYP19A1ATAD2BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL4997030 | 0.76 | ALDH1A1 (0.37) | PGRADRA2AADRA2BADRA2C | |
| SCHEMBL5505351 | 0.75 | ATAD2 (0.56) | CYP19A1ATAD2BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL5116351 | 0.73 | ATAD2 (0.57) | CYP19A1ATAD2BMPR1BBMPR1ATGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781643-A1 | OXINDOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006016220-A1 | OXINDOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-16 | — | — | WO | disclosed |