SCHEMBL551122

SCHEMBL551122

Nc1ccc(S(=O)(=O)Oc2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.56
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
CA9 Q16790 3/20 0.52
MAOA P21397 1/20 0.48
KMT2A Q03164 1/20 0.47
TSHR P16473 3/20 0.46
LMNA P02545 2/20 0.46
MPO P05164 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
HTR6 P50406 1/20 0.46
SOS1 Q07889 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.45
MAPT P10636 3/20 0.45
CA12 O43570 1/20 0.45
USP2 O75604 1/20 0.45
CA4 P22748 1/20 0.45
CA6 P23280 1/20 0.45
CA5A P35218 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formaldehyde SCHEMBL8381775 0.96 TDP1 (0.53) TDP1CA1CA2CA9MAOA
SCHEMBL1459166 0.92 TDP1 (0.67) TDP1CA1CA2CA9MAOA
SCHEMBL11526117 0.90 TSHR (0.52) TDP1CA1CA2CA9KMT2A
Biphenyl SCHEMBL28331957 0.87 TDP1 (0.61) TDP1CA1CA2CA9MAOA
SCHEMBL19146 0.85 TDP1 (0.73) TDP1CA1CA2CA9KMT2A
SCHEMBL7981247 0.85 TDP1 (0.73) TDP1CA1CA2CA9KMT2A
SCHEMBL31202967 0.84 ALDH1A1 (0.56) TDP1CA1CA2CA9MAOA
SCHEMBL19470809 0.83 HTR6 (0.47) TDP1CA1CA2CA9KMT2A
SCHEMBL1674227 0.83 TDP1 (0.70) TDP1CA1CA2CA9KMT2A
SCHEMBL28934632 0.83 TDP1 (0.70) TDP1CA1CA2CA9KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101478977-B Treatment of neurodegenerative diseases VELACOR THERAPEUTICS PTY LTD 2013-03-27 CN disclosed
US-8178271-B2 Polymer having a sulfonic group or a sulfonate group and an amide group and method of producing same CANON KABUSHIKI KAISHA (JP) 2012-05-15 US disclosed
US-8110329-B2 Charge controlling agent and toner CANON KABUSHIKI KAISHA (JP) 2012-02-07 US disclosed
US-8067136-B2 Charge control agent, toner, image forming method, and image forming apparatus CANON KABUSHIKI KAISHA (JP) 2011-11-29 US disclosed
EP-2292670-A2 Charge control agent, toner, image forming method, and image forming apparatus Canon Kabushiki Kaisha (JP) 2011-03-09 EP disclosed
US-20100233610-A1 POLYMER HAVING A SULFONIC GROUP OR A SULFONATE GROUP AND AN AMIDE GROUP AND METHOD OF PRODUCING SAME CANON KABUSHIKI KAISHA (JP) 2010-09-16 US disclosed
US-7795363-B2 Polymer having a sulfonic group or a sulfonate group and an amide group and method of producing same CANON KABUSHIKI KAISHA (JP) 2010-09-14 US disclosed
US-20100121023-A1 POLYMER HAVING A SULFONIC GROUP OR A SULFONATE GROUP AND AN AMIDE GROUP AND METHOD OF PRODUCING SAME CANON KABUSHIKI KAISHA (JP) 2010-05-13 US disclosed
EP-2184645-A2 Charge control agent, toner, image forming method and image forming apparatus Canon Kabushiki Kaisha (JP) 2010-05-12 EP disclosed
EP-1758949-B1 POLYHYDROXYALKANOATE HAVING VINYL GROUP, ESTER GROUP, CARBOXYL GROUP AND SULFONIC ACID GROUP, AND PRODUCTION METHOD THEREOF CANON KK (JP) 2010-01-13 EP disclosed
EP-0013609-A1 Water-soluble monoazo dyes of the benzene azo indole series, their preparation and their application for the colouration of polyamide textile materials IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1980-07-23 EP disclosed
US-4201707-A Methine dyestuffs containing a phenyl azo group BAYER AKTIENGESELLSCHAFT (DE) 1980-05-06 US disclosed
US-4172089-A COMPLEMENT INHIBITOR TRI- OR HEXA-PHENYL ESTER INTERMEDIATES AMERICAN CYANAMID COMPANY (US) 1979-10-23 US disclosed
US-4156086-A INTERMEDIATES FOR AZO DYES BAYER AKTIENGESELLSCHAFT (DE) 1979-05-22 US disclosed
US-4138570-A METHINE DYE BAYER AKTIENGESELLSCHAFT (DE) 1979-02-06 US disclosed
US-4136033-A DIAZO COUPLERS SANDOZ LTD. (CH) 1979-01-23 US disclosed
US-4117003-A COMPLEMENT INHIBITORS AMERICAN CYANAMID COMPANY (US) 1978-09-26 US disclosed
US-4080322-A WATER SOLUBLE DYES FOR LEATHER, PAPER, AND NON-WOVEN TEXTILES SANDOZ LTD. (CH) 1978-03-21 US disclosed
US-4038268-A DIAZOTIZATION, COUPLING BAYER AKTIENGESELLSCHAFT (DT) 1977-07-26 US disclosed
US-4006128-A CELLULOSE ACETATES, VINYL POLYMERS, POLYOLEFINS, POLYESTERS BAYER AKTIENGESELLSCHAFT (DT) 1977-02-01 US disclosed