Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL740804 | 1.00 | BTK (0.37) | BTKMAOBKDM1AMAOAEPHX1 | |
| SCHEMBL1504585 | 1.00 | BTK (0.37) | BTKMAOBKDM1AMAOAEPHX1 | |
| SCHEMBL1504166 | 0.86 | BTK (0.39) | BTKMAOBKDM1AMAOAEPHX1 | |
| SCHEMBL3326571 | 0.83 | BTK (0.46) | BTKMAOBKDM1AEPHX1KMT2A | |
| SCHEMBL14169680 | 0.83 | BTK (0.46) | BTKMAOBKDM1AEPHX1KMT2A | |
| SCHEMBL3327036 | 0.83 | BTK (0.46) | BTKMAOBKDM1AEPHX1KMT2A | |
| SCHEMBL744166 | 0.81 | MAOB (0.35) | BTKMAOBKDM1AMAOAEPHX1 | |
| SCHEMBL1503980 | 0.78 | MAOB (0.37) | MAOBKDM1AMAOAKMT2AL3MBTL1 | |
| SCHEMBL1503975 | 0.77 | CPB1 (0.44) | MAOBKDM1AEPHX1KMT2AL3MBTL1 | |
| SCHEMBL23369647 | 0.76 | BTK (0.47) | BTKMAOBKDM1AEPHX1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007106759-A | OPTICALLY ACTIVE DIAMINE DERIVATIVE AND METHOD FOR PRODUCING THE SAME | DAI ICHI SEIYAKU CO LTD | 2007-04-26 | — | — | JP | disclosed |