Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 4/20 | 0.50 |
| ▸ | CNR2 | P34972 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | F7 | P08709 | 2/20 | 0.45 |
| ▸ | F3 | P13726 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26371776 | 1.00 | ALDH1A1 (0.51) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL3702735 | 0.94 | EPHX2 (0.51) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL3697602 | 0.94 | EPHX2 (0.51) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL3699655 | 0.91 | MAPT (0.53) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL26371774 | 0.91 | MAPT (0.56) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL26371778 | 0.91 | EPHX2 (0.48) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL9441213 | 0.91 | MAPT (0.56) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL291932 | 0.87 | MAPT (0.55) | ALDH1A1ALOX15HSD17B10TDP1EPHX2 | |
| SCHEMBL16884634 | 0.87 | MAPT (0.55) | ALDH1A1ALOX15HSD17B10TDP1EPHX2 | |
| SCHEMBL2825440 | 0.87 | MAPT (0.55) | ALDH1A1ALOX15HSD17B10TDP1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309698-B1 | A CYTOCHROME P450 ENZYME ASSOCIATED WITH THE SYNTHESIS OF DELTA-12 -EPOXY GROUPS IN FATTY ACIDS OF PLANTS | DU PONT (US) | 2007-04-18 | — | — | EP | disclosed |
| US-20040139499-A1 | Cytochrome P450 dependent enzyme associated with the synthesis of the epoxy group of vernolic acid | CAHOON EDGAR B (US) | 2004-07-15 | — | — | US | disclosed |
| EP-1309698-A2 | A CYTOCHROME P450 ENZYME ASSOCIATED WITH THE SYNTHESIS OF DELTA-12 -EPOXY GROUPS IN FATTY ACIDS OF PLANTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-05-14 | — | — | EP | disclosed |
| US-20030066103-A1 | Cytochrome P450 enzyme associated with the synthesis of delta12-epoxy groups in fatty acids of plants | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-04-03 | — | — | US | disclosed |
| WO-2002008269-A2 | A CYTOCHROME P450 ENZYME ASSOCIATED WITH THE SYNTHESIS OF Δ12-EPOXY GROUPS IN FATTY ACIDS OF PLANTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-01-31 | — | — | WO | disclosed |