SCHEMBL2825440

SCHEMBL2825440

CCCCCC1OC1C/C=C\CCCCCCCC(=O)OC

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.55
EPHX2 P34913 2/20 0.54
CNR2 P34972 1/20 0.47
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
HKDC1 Q2TB90 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
SAE1 Q9UBE0 1/20 0.47
UBA2 Q9UBT2 1/20 0.47
ALOX5 P09917 3/20 0.46
OXER1 Q8TDS5 1/20 0.46
PTGER4 P35408 1/20 0.44
PTGER3 P43115 1/20 0.44
GMNN O75496 1/20 0.44
USP2 O75604 1/20 0.44
LMNA P02545 1/20 0.44
CYP1A2 P05177 1/20 0.44
POLB P06746 1/20 0.44
CYP2C9 P11712 1/20 0.44
ALOX15 P16050 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19127905 1.00 MAPT (0.55) MAPTEPHX2CNR2KDM4EALDH1A1
SCHEMBL29508172 1.00 MAPT (0.55) MAPTEPHX2CNR2KDM4EALDH1A1
SCHEMBL5084837 1.00 MAPT (0.55) MAPTEPHX2CNR2KDM4EALDH1A1
SCHEMBL5204684 1.00 MAPT (0.55) MAPTEPHX2CNR2KDM4EALDH1A1
SCHEMBL16884634 1.00 MAPT (0.55) MAPTEPHX2CNR2KDM4EALDH1A1
SCHEMBL291932 1.00 MAPT (0.55) MAPTEPHX2CNR2KDM4EALDH1A1
SCHEMBL835295 1.00 MAPT (0.55) MAPTEPHX2CNR2KDM4EALDH1A1
SCHEMBL2825437 1.00 MAPT (0.55) MAPTEPHX2CNR2KDM4EALDH1A1
SCHEMBL835150 1.00 MAPT (0.55) MAPTEPHX2CNR2KDM4EALDH1A1
SCHEMBL21376096 0.91 MAPT (0.64) MAPTEPHX2CNR2ALDH1A1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399514-A1 BIOSOLVENTS USEFUL FOR IMPROVED ASPHALT PRODUCTS UTILIZING RECYCLED ASPHALT PAVEMENT OR OTHER BRITTLE ASPHALT BINDERS SUCH AS VACUUM TOWER BOTTOM UNIV IOWA STATE RES FOUND INC (US) 2023-12-14 US disclosed
US-11826345-B2 Dosing regimens of PKC activators Synaptogenix, Inc. (US) 2023-11-28 US disclosed
US-11826345-B2 Dosing regimens of PKC activators Synaptogenix, Inc. (US) 2023-11-28 US disclosed
US-11773265-B2 Biosolvents useful for improved asphalt products utilizing recycled asphalt pavement or other brittle asphalt binders such as vacuum tower bottom IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2023-10-03 US disclosed
US-20210023048-A1 DOSING REGIMENS OF PKC ACTIVATORS COGNITIVE RESEARCH ENTERPRISES, INC. (US) 2021-01-28 US disclosed
US-10821079-B2 PKC activators and combinations thereof COGNITIVE RESEARCH ENTERPRISES, INC. (US) 2020-11-03 US disclosed
US-20180217163-A1 TREATMENT OF NEURODEGENERATIVE CONDITIONS USING PKC ACTIVATORS AFTER DETERMINING THE PRESENCE OF THE APOE4 ALLELE WEST VIRGINIA UNIVERSITY 2018-08-02 US disclosed
US-20170283615-A1 IMPROVED ASPHALT PRODUCTS AND MATERIALS AND METHODS OF PRODUCING THEM IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2017-10-05 US disclosed
US-20170283615-A1 IMPROVED ASPHALT PRODUCTS AND MATERIALS AND METHODS OF PRODUCING THEM IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2017-10-05 US disclosed
WO-2016033605-A1 IMPROVED ASPHALT PRODUCTS AND MATERIALS AND METHODS OF PRODUCING THEM IOWA STATE UNIVERSITY RESEARCH FOUNDATION INC. (US) 2016-03-03 WO disclosed
EP-2242361-A2 USE OF SURFACTANTS FOR MITIGATING DAMAGE TO PLANTS FROM PESTS Bjarn, Llc (US) 2010-10-27 EP disclosed
EP-2242369-A1 USE OF BIO-DERIVED SURFACTANTS FOR MITIGATING DAMAGE TO PLANTS FROM PESTS Bjarn, Llc (US) 2010-10-27 EP disclosed
WO-2009091572-A2 USE OF SURFACTANTS FOR MITIGATING DAMAGE TO PLANTS FROM PESTS BJARN, LLC (US) 2009-07-23 WO disclosed
WO-2009091564-A1 USE OF BIO-DERIVED SURFACTANTS FOR MITIGATING DAMAGE TO PLANTS FROM PESTS BJARN, LLC (US) 2009-07-23 WO disclosed
US-20090186761-A1 Use of bio-derived surfactants for mitigating damage to plants from pests CLEARESO, LLC 2009-07-23 US disclosed
US-20090186767-A1 Use of surfactants for mitigating damage to plants from pests CLEARESO, LLC 2009-07-23 US disclosed
US-6903052-B2 Nematicidal compositions and methods DIVERGENCE, INC. (US) 2005-06-07 US disclosed
US-6887900-B2 Nematicidal compositions and methods DIVERGENCE, INC. (US) 2005-05-03 US disclosed
US-20030176402-A1 Nematicidal compositions and methods MONSANTO TECHNOLOGY LLC 2003-09-18 US disclosed
US-20030166714-A1 Nematicidal compositions and methods MONSANTO TECHNOLOGY LLC 2003-09-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170283615-A1 IMPROVED ASPHALT PRODUCTS AND MATERIALS AND METHODS OF PRODUCING THEM PTAR1, LCAT, ANAPC7 MAPT 4/4885EPHX2 104/4885CNR2 3264/4885
US-10821079-B2 PKC activators and combinations thereof PRKCH, PRKCB, PRKCA MAPT 4095/4885EPHX2 3007/4885CNR2 4120/4885
US-20090186767-A1 Use of surfactants for mitigating damage to plants from pests FAAH, SGMS2, FASN MAPT 2873/4885EPHX2 238/4885CNR2 355/4885
US-20180217163-A1 TREATMENT OF NEURODEGENERATIVE CONDITIONS USING PKC ACTIVATORS AFTER DETERMINING THE PRESENCE OF THE APOE4 ALLELE PRKCH, PRKAR2A, PRKCA MAPT 188/4885EPHX2 1636/4885CNR2 2787/4885
US-20210023048-A1 DOSING REGIMENS OF PKC ACTIVATORS PRKCA, PRKCH, PRKCQ MAPT 405/4885EPHX2 2926/4885CNR2 3123/4885
US-20030166714-A1 Nematicidal compositions and methods SCD, FADS2, ELOVL3 MAPT 4347/4885EPHX2 230/4885CNR2 229/4885
US-20090186761-A1 Use of bio-derived surfactants for mitigating damage to plants from pests SGMS2, SGMS1, PHOSPHO1 MAPT 2855/4885EPHX2 336/4885CNR2 436/4885
US-20030176402-A1 Nematicidal compositions and methods FADS2, FASN, SCD MAPT 4351/4885EPHX2 150/4885CNR2 202/4885
US-11826345-B2 Dosing regimens of PKC activators PRKCA, PRKCH, PRKCQ MAPT 405/4885EPHX2 2926/4885CNR2 3123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.