⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5509509 | 0.71 | — | — | |
| SCHEMBL11664731 | 0.69 | — | — | |
| SCHEMBL11664729 | 0.69 | — | — | |
| SCHEMBL12320643 | 0.68 | — | — | |
| SCHEMBL18184492 | 0.65 | LMNA (0.33) | — | |
| SCHEMBL5508618 | 0.65 | CHIA (0.31) | — | |
| SCHEMBL12854175 | 0.63 | — | — | |
| SCHEMBL20368331 | 0.61 | LOXL2 (0.37) | — | |
| SCHEMBL27624078 | 0.61 | HPGD (0.36) | — | |
| SCHEMBL5508163 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223755-B2 | Hydroxymorpholinone derivative and medicinal use thereof | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2007-05-29 | — | — | US | disclosed |
| US-20050176704-A1 | Hydroxymorpholinone derivative and medicinal use thereof | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2005-08-11 | — | — | US | disclosed |