SCHEMBL5512445

SCHEMBL5512445

O=C(O)CNc1ncccc1OCC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
POLB P06746 1/20 0.47
GLA P06280 1/20 0.47
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 2/20 0.45
HPGD P15428 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
PTGDR2 Q9Y5Y4 1/20 0.45
PPIA P62937 3/20 0.45
TBXAS1 P24557 2/20 0.44
CASP1 P29466 1/20 0.43
HSD17B10 Q99714 1/20 0.43
EGLN2 Q96KS0 1/20 0.42
FTO Q9C0B1 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
ALOX15 P16050 1/20 0.42
MAPT P10636 1/20 0.41
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2179962 0.77 DHODH (0.58) L3MBTL1SMN1; SMN2KDM4EALDH1A1HPGD
SCHEMBL1669341 0.77 SHMT2 (0.45) KDM4EALDH1A1HPGDHSD17B10EGLN2
SCHEMBL15119425 0.77 EGLN2 (0.44) L3MBTL1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL5516797 0.75 L3MBTL1 (0.56) L3MBTL1SMN1; SMN2POLBGLAKDM4E
SCHEMBL9965997 0.75 L3MBTL1 (0.56) L3MBTL1SMN1; SMN2POLBGLAKDM4E
SCHEMBL16742738 0.75 L3MBTL1 (0.51) L3MBTL1SMN1; SMN2POLBGLAKDM4E
SCHEMBL5429041 0.75 L3MBTL1 (0.51) L3MBTL1SMN1; SMN2POLBGLAKDM4E
SCHEMBL16741104 0.75 PTGDR2 (0.53) L3MBTL1SMN1; SMN2POLBGLAKDM4E
SCHEMBL5524278 0.75 KDM4E (0.54) L3MBTL1SMN1; SMN2POLBGLAKDM4E
SCHEMBL30680090 0.75 PTGDR2 (0.53) L3MBTL1SMN1; SMN2POLBGLAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470258-B1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2013-08-28 EP disclosed
US-7250456-B2 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2007-07-31 US disclosed
US-20050148702-A1 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2005-07-07 US disclosed
EP-1470258-A1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL Ledertechnik GmbH (DE) 2004-10-27 EP disclosed
WO-2003064707-A1 COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2003-08-07 WO disclosed