Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 11/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.53 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2844099 | 0.85 | ANO1 (0.50) | ANO1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL31723133 | 0.83 | MAPT (0.79) | ANO1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL22284779 | 0.83 | MAPT (0.79) | ANO1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL31723174 | 0.82 | MAPT (0.61) | ANO1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL20923370 | 0.82 | MAPT (0.61) | ANO1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL3535900 | 0.81 | KDM4E (0.82) | ANO1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL14710668 | 0.81 | ANO1 (0.68) | ANO1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL30142386 | 0.80 | KDM4E (0.62) | ANO1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL14788524 | 0.80 | KDM4E (0.62) | ANO1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL11734827 | 0.79 | ADORA3 (0.59) | KDM4EALDH1A1HPGDMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7265152-B2 | Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases | VIROPHARMA INCORPORATED (US) | 2007-09-04 | — | — | US | claimed |