Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21173 | 0.82 | PAOX (0.41) | PAOXAPOBEC3AAPOBEC3GALDH1A1KDM5A | |
| Hydrochloric Acid SCHEMBL1396446 | 0.80 | PAOX (0.40) | PAOXAPOBEC3AAPOBEC3GALDH1A1KDM5A | |
| SCHEMBL888049 | 0.80 | NPSR1 (0.41) | PAOXAPOBEC3AAPOBEC3GALDH1A1KDM5A | |
| SCHEMBL3933480 | 0.79 | PAOX (0.44) | PAOXAPOBEC3AAPOBEC3GALDH1A1KDM5A | |
| SCHEMBL11417088 | 0.78 | GAA (0.39) | PAOXAPOBEC3AAPOBEC3GALDH1A1KDM5A | |
| SCHEMBL6143382 | 0.78 | PAOX (0.39) | PAOXAPOBEC3AAPOBEC3GALDH1A1KDM5A | |
| Acetic Acid SCHEMBL9812829 | 0.78 | PAOX (0.42) | PAOXAPOBEC3AAPOBEC3GALDH1A1KDM5A | |
| SCHEMBL2373700 | 0.78 | KDM5A (0.42) | PAOXAPOBEC3AAPOBEC3GALDH1A1KDM5A | |
| Chloromethane SCHEMBL2515652 | 0.78 | PAOX (0.39) | PAOXAPOBEC3AAPOBEC3GALDH1A1KDM5A | |
| SCHEMBL15233992 | 0.77 | PAOX (0.38) | PAOXAPOBEC3AAPOBEC3GALDH1A1KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761525-A1 | THIOETHER DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-03-14 | — | — | EP | claimed |
| WO-2005116019-A1 | THIOETHER DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-12-08 | — | — | WO | claimed |