Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.43 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.37 |
| ▸ | BID | P55957 | 4/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.37 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | PRKCH | P24723 | 1/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL466771 | 0.87 | FOLH1 (0.50) | FOLH1HMGB1ALOX15CLCN2 | |
| SCHEMBL5512212 | 0.82 | METAP2 (0.34) | — | |
| SCHEMBL1582331 | 0.82 | EGFR (0.32) | — | |
| SCHEMBL9338483 | 0.82 | FOLH1 (0.49) | FOLH1HMGB1BIDMCL1BCL2L1 | |
| SCHEMBL5526601 | 0.81 | EGFR (0.31) | — | |
| SCHEMBL5531082 | 0.80 | EGFR (0.33) | — | |
| SCHEMBL6057622 | 0.79 | EGFR (0.36) | — | |
| SCHEMBL5516223 | 0.79 | EGFR (0.30) | — | |
| SCHEMBL5525472 | 0.79 | LDHA (0.32) | — | |
| SCHEMBL5517030 | 0.79 | DPP4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7282601-B2 | Dicarboxylic diester, process for producing the same, and refrigerating machine lubricating oil comprising the ester | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2007-10-16 | — | — | US | disclosed |
| US-7271282-B1 | Dicarboxylic diester, process for producing the same, and refrigerating machine lubricating oil comprising the ester | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2007-09-18 | — | — | US | disclosed |
| US-6841522-B2 | Lubricant compositions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 2005-01-11 | — | — | US | disclosed |
| US-4608277-A | POLYURETHANE-POLYUREA CASING | CASELLA AKTIENGESELLSCHAFT (DE) | 1986-08-26 | — | — | US | disclosed |
| US-4547429-A | Encapsulated salts of acid particles wherein the salt particles are surrounded by a polyurethane/polyurea casing | CASSELLA AKTIENGESELLSCHAFT (DE) | 1985-10-15 | — | — | US | disclosed |