SCHEMBL5513503

SCHEMBL5513503

CNc1cc(F)c(F)c(NC)c1F

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22421805 0.85 RAPGEF4 (0.37) RAPGEF4
SCHEMBL5511097 0.81
SCHEMBL5514156 0.81 RAPGEF4 (0.32) RAPGEF4
SCHEMBL27275061 0.78 ADRA2A (0.36)
SCHEMBL5513090 0.75 RAPGEF4 (0.39) RAPGEF4
SCHEMBL5507115 0.75 RAPGEF4 (0.34) RAPGEF4
SCHEMBL5517348 0.74 ADRA2A (0.36) RAPGEF4
SCHEMBL5510357 0.74 RAPGEF4 (0.31) RAPGEF4
SCHEMBL5514290 0.73 HSD17B10 (0.34) RAPGEF4
SCHEMBL7979895 0.73 HSD17B10 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7208559-B2 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2007-04-24 US disclosed
US-20060135712-A1 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2006-06-22 US disclosed