Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5507483 | 0.80 | ESR1 (0.38) | ESR1ESR2TRPV1 | |
| SCHEMBL5522365 | 0.76 | ESR1 (0.45) | ESR1ESR2CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL5513095 | 0.74 | ESR1 (0.37) | ESR1ESR2TRPV1CYP17A1CYP11B1 | |
| SCHEMBL14158134 | 0.73 | ESR1 (0.42) | ESR1ESR2CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL5514312 | 0.73 | ESR1 (0.42) | ESR1ESR2CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL5517867 | 0.71 | RAPGEF4 (0.35) | — | |
| SCHEMBL1487928 | 0.71 | TNIK (0.41) | ESR1ESR2CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL27639116 | 0.70 | ESR1 (0.54) | ESR1ESR2 | |
| SCHEMBL5517876 | 0.68 | MEP1B (0.37) | ESR1ESR2 | |
| SCHEMBL1637217 | 0.68 | RAPGEF4 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208559-B2 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2007-04-24 | — | — | US | disclosed |
| US-20060135712-A1 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2006-06-22 | — | — | US | disclosed |