Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5509172 | 1.00 | AR (0.40) | ARCCR1CCR2GRM2GSK3A | |
| SCHEMBL5509169 | 1.00 | AR (0.40) | ARCCR1CCR2GRM2GSK3A | |
| SCHEMBL9892985 | 0.85 | PTGER2 (0.48) | CCR1CCR2GRM2GSK3AGSK3B | |
| SCHEMBL14509051 | 0.81 | KDM1A (0.37) | CCR1CCR2GRM2GSK3AGSK3B | |
| SCHEMBL5356806 | 0.78 | IDH1 (0.42) | ARCCR1CCR2GRM2GSK3A | |
| SCHEMBL5355389 | 0.78 | IDH1 (0.42) | ARCCR1CCR2GRM2GSK3A | |
| SCHEMBL10004264 | 0.73 | BCHE (0.40) | CCR1CCR2ALDH1A1MAPTATM | |
| SCHEMBL16480454 | 0.70 | NPC1 (0.49) | ARCCR1CCR2GRM2GSK3A | |
| SCHEMBL5370694 | 0.70 | KDM1A (0.35) | ARGRM2GSK3AGSK3BMAPT | |
| SCHEMBL5359605 | 0.70 | KDM1A (0.35) | ARGRM2GSK3AGSK3BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223859-B2 | Method for producing (R)-3-[4-(trifluoromethyl) phenylamino]-pentanoic acid amide derivative | PFIZER INC. (US) | 2007-05-29 | — | — | US | claimed |
| EP-1604975-A1 | PROCESSES FOR PRODUCTION OF (R)-3- 4-(TRIFLUOROMETHYL)- PHEN YLAMINO PENTANAMIDE DERIVATIVES | KANEKA CORPORATION (JP) | 2005-12-14 | — | — | EP | claimed |
| US-20040199005-A1 | Method for producing (R) -3- [4- (trifluoromethyl) phenylamino] -pentanoic acid amide derivative | KANEKA CORPORATION (JP) | 2004-10-07 | — | — | US | claimed |
| US-7223859-B2 | Method for producing (R)-3-[4-(trifluoromethyl) phenylamino]-pentanoic acid amide derivative | PFIZER INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223859-B2 | Method for producing (R)-3-[4-(trifluoromethyl) phenylamino]-pentanoic acid amide derivative | PFIZER INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223859-B2 | Method for producing (R)-3-[4-(trifluoromethyl) phenylamino]-pentanoic acid amide derivative | PFIZER INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223859-B2 | Method for producing (R)-3-[4-(trifluoromethyl) phenylamino]-pentanoic acid amide derivative | PFIZER INC. (US) | 2007-05-29 | — | — | US | disclosed |
| EP-1604975-A4 | PROCESSES FOR PRODUCTION OF (R)-3- 4-(TRIFLUOROMETHYL)- PHEN YLAMINO PENTANAMIDE DERIVATIVES | KANEKA CORP (JP) | 2006-11-02 | — | — | EP | disclosed |
| EP-1604975-A1 | PROCESSES FOR PRODUCTION OF (R)-3- 4-(TRIFLUOROMETHYL)- PHEN YLAMINO PENTANAMIDE DERIVATIVES | KANEKA CORPORATION (JP) | 2005-12-14 | — | — | EP | disclosed |
| EP-1604975-A1 | PROCESSES FOR PRODUCTION OF (R)-3- 4-(TRIFLUOROMETHYL)- PHEN YLAMINO PENTANAMIDE DERIVATIVES | KANEKA CORPORATION (JP) | 2005-12-14 | — | — | EP | disclosed |
| US-20040199005-A1 | Method for producing (R) -3- [4- (trifluoromethyl) phenylamino] -pentanoic acid amide derivative | KANEKA CORPORATION (JP) | 2004-10-07 | — | — | US | disclosed |
| US-20040199005-A1 | Method for producing (R) -3- [4- (trifluoromethyl) phenylamino] -pentanoic acid amide derivative | KANEKA CORPORATION (JP) | 2004-10-07 | — | — | US | disclosed |
| WO-2004083166-A1 | PROCESSES FOR PRODUCTION OF (R)-3-[4-(TRIFLUOROMETHYL)- PHENYLAMINO]PENTANAMIDE DERIVATIVES | KANEKA CORPORATION (JP) | 2004-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040199005-A1 | Method for producing (R) -3- [4- (trifluoromethyl) phenylamino] -pentanoic acid amide derivative | CETP, PCTP, MTTP | AR 4000/4885CCR1 3003/4885CCR2 2379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.