SCHEMBL5513933

SCHEMBL5513933

NC[C@@H]1CN(c2ccc(N3CCOCC3)c(F)c2)C(=O)O1

nearest known ligand 0.69

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 13/20 0.69
▸ MAOA P21397 6/20 0.69
▸ PTGS1 P23219 2/20 0.69
▸ SDHA P31040 2/20 0.69
▸ LMNA P02545 1/20 0.69
▸ CALML3 P27482 1/20 0.69
▸ F10 P00742 4/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1336215 1.00 MAOB (0.69) MAOBMAOAPTGS1SDHALMNA
SCHEMBL76846 1.00 MAOB (0.69) MAOBMAOAPTGS1SDHALMNA
SCHEMBL29439547 1.00 MAOB (0.69) MAOBMAOAPTGS1SDHALMNA
Acetic Acid SCHEMBL1338391 0.94 MAOB (0.74) MAOBMAOAPTGS1SDHALMNA
Acetic Acid SCHEMBL1338393 0.94 MAOB (0.74) MAOBMAOAPTGS1SDHALMNA
SCHEMBL3523994 0.91 F10 (0.59) MAOBMAOAPTGS1SDHALMNA
SCHEMBL3523989 0.91 F10 (0.59) MAOBMAOAPTGS1SDHALMNA
SCHEMBL12176864 0.89 MAOB (0.70) MAOBMAOAPTGS1SDHALMNA
SCHEMBL3525075 0.89 F10 (0.58) MAOBMAOAPTGS1SDHALMNA
SCHEMBL13404010 0.89 F10 (0.58) MAOBMAOAPTGS1SDHALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1745028-A2 SOLID FORMS OF LINEZOLID AND PROCESSES FOR PREPARATION THEREOF Teva Pharmaceutical Industries Ltd (IL) 2007-01-24 — — EP claimed
WO-2006110155-A1 SOLID FORMS OF LINEZOLID AND PROCESSES FOR PREPARATION THEREOF TEVA PHARMACEUTICAL INDUSTRIES LTD (IL) 2006-10-19 — — WO claimed
US-20060111350-A1 Solid forms of linezolid and processes for preparation thereof TEVA PHARMACEUTICALS USA, INC. 2006-05-25 — — US claimed
CN-119912441-A Novel oxazolidinone compound and anti-infection application thereof 安徽医科大学第一附属医院 2025-05-02 — — CN disclosed
EP-2917189-B1 PROCESS FOR MAKING LINEZOLID SYNTHON BV (NL) 2016-08-17 — — EP disclosed
US-9376407-B2 Process for preparation of Linezolid and its novel intermediates LEE PHARMA LIMITED (IN) 2016-06-28 — — US disclosed
US-9376407-B2 Process for preparation of Linezolid and its novel intermediates LEE PHARMA LIMITED (IN) 2016-06-28 — — US disclosed
EP-2595968-B1 NOVEL PROCESS FOR PREPARATION OF LINEZOLID AND ITS NOVEL INTERMEDIATES LEE PHARMA LTD (IN) 2015-09-09 — — EP disclosed
US-9012631-B2 1,3-oxazolidine-2-one-like compound, preparation method and uses thereof YABANG PHARMACEUTICAL CO., LTD (CN) 2015-04-21 — — US disclosed
US-20140171640-A1 1,3-OXAZOLIDINE-2-ONE-LIKE COMPOUND, PREPARATION METHOD AND USES THEREOF YABANG PHARMACEUTICAL CO., LTD (CN) 2014-06-19 — — US disclosed
WO-2014071990-A1 PROCESS FOR MAKING LINEZOLID SYNTHON BV (NL) 2014-05-15 — — WO disclosed
EP-1745028-A2 SOLID FORMS OF LINEZOLID AND PROCESSES FOR PREPARATION THEREOF Teva Pharmaceutical Industries Ltd (IL) 2007-01-24 — — EP disclosed
WO-2006110155-A1 SOLID FORMS OF LINEZOLID AND PROCESSES FOR PREPARATION THEREOF TEVA PHARMACEUTICAL INDUSTRIES LTD (IL) 2006-10-19 — — WO disclosed
US-20060111350-A1 Solid forms of linezolid and processes for preparation thereof TEVA PHARMACEUTICALS USA, INC. 2006-05-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060111350-A1 Solid forms of linezolid and processes for preparation thereof F9, Q6ZSR9, TBCD MAOB 2551/4885MAOA 1756/4885PTGS1 4164/4885
US-20140171640-A1 1,3-OXAZOLIDINE-2-ONE-LIKE COMPOUND, PREPARATION METHOD AND USES THEREOF OXA1L, CYP2C9, CYP1B1 MAOB 493/4885MAOA 1038/4885PTGS1 897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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