Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 13/20 | 0.74 |
| ▸ | MAOA | P21397 | 7/20 | 0.74 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.74 |
| ▸ | SDHA | P31040 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | CALML3 | P27482 | 1/20 | 0.74 |
| ▸ | F10 | P00742 | 4/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL1338391 | 1.00 | MAOB (0.74) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL5513933 | 0.94 | MAOB (0.69) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL1336215 | 0.94 | MAOB (0.69) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL76846 | 0.94 | MAOB (0.69) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL29439547 | 0.94 | MAOB (0.69) | MAOBMAOAPTGS1SDHALMNA | |
| Linezolid SCHEMBL2322867 | 0.86 | MAOB (0.89) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL1498726 | 0.85 | MAOB (0.61) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL28425877 | 0.85 | MAOB (0.56) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL28425878 | 0.85 | MAOB (0.56) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL12126903 | 0.85 | MAOB (0.72) | MAOBMAOAPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658789-B2 | Method for preparing linezolid and intermediates thereof | LIANHE CHEMICAL TECHNOLOGY CO., LTD. (CN) | 2014-02-25 | — | — | US | disclosed |
| EP-2388251-B1 | METHOD FOR PREPARING LINEZOLID AND INTERMEDIATES THEREOF | LIANHE CHEMICAL TECHNOLOGY CO LTD (CN) | 2013-08-28 | — | — | EP | disclosed |
| EP-2388251-A1 | METHOD FOR PREPARING LINEZOLID AND INTERMEDIATES THEREOF | Lianhe Chemical Technology Co., Ltd. (CN) | 2011-11-23 | — | — | EP | disclosed |
| US-20110275805-A1 | METHOD FOR PREPARING LINEZOLID AND INTERMEDIATES THEREOF | LIANHE CHEMICAL TECHNOLOGY CO., LTD. (CN) | 2011-11-10 | — | — | US | disclosed |
| US-8038543-B2 | Golf swing training device | CAPESIUS DEAN C | 2011-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275805-A1 | METHOD FOR PREPARING LINEZOLID AND INTERMEDIATES THEREOF | HDAC9, KAT5, ACMSD | MAOB 2466/4885MAOA 2149/4885PTGS1 3624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.