SCHEMBL5514072

SCHEMBL5514072

Oc1c(F)ccc2c(NC(F)(F)F)cccc12

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.35
ERN1 O75460 1/20 0.34
NR3C1 P04150 5/20 0.33
PGR P06401 4/20 0.33
AR P10275 2/20 0.33
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
KDM4E B2RXH2 3/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
MPI P34949 1/20 0.32
TRPV1 Q8NER1 1/20 0.32
ALB P02768 1/20 0.31
P2RX1 P51575 1/20 0.31
P2RX7 Q99572 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5516167 0.80 KDM4E (0.32) IDO1MEN1KMT2ANPC1RAB9A
SCHEMBL5512986 0.79 IDO1 (0.48) IDO1ERN1NR3C1PGRAR
SCHEMBL5513484 0.78 CA3 (0.31) ERN1
SCHEMBL5513205 0.77
SCHEMBL5511502 0.77 MEN1 (0.30) MEN1KMT2ANPC1RAB9AKDM4E
SCHEMBL5509646 0.77
SCHEMBL5507012 0.75 MAPT (0.42) IDO1MEN1KMT2ANPC1RAB9A
SCHEMBL20498277 0.75 RAB9A (0.44) ERN1MEN1KMT2ANPC1RAB9A
SCHEMBL8026725 0.73 KMT2A (0.49) MEN1KMT2ANPC1RAB9AKDM4E
SCHEMBL5513985 0.72 ERN1 (0.42) ERN1MEN1KMT2AKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7208559-B2 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2007-04-24 US disclosed
US-20060135712-A1 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2006-06-22 US disclosed