SCHEMBL15065239

SCHEMBL15065239

Clc1ccc2c(C#Cc3ccccc3)c3c(Cl)cccc3c(C#Cc3ccccc3)c2c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 4/20 0.36
APP P05067 1/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.34
ATM Q13315 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ASIC3 Q9UHC3 1/20 0.33
AKR1C2 P52895 1/20 0.33
AKR1C1 Q04828 1/20 0.33
FLT3 P36888 1/20 0.32
PTPRC P08575 1/20 0.32
PTPN2 P17706 1/20 0.32
PTPN1 P18031 1/20 0.32
PTPN6 P29350 1/20 0.32
PTPN9 P43378 1/20 0.32
DUSP3 P51452 1/20 0.32
PTPN11 Q06124 1/20 0.32
PTPN22 Q9Y2R2 1/20 0.32
GRM5 P41594 1/20 0.32
KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL432731 0.89 APP (0.43) GRM4APPATMTDP1L3MBTL1
SCHEMBL29365692 0.89 APP (0.43) GRM4APPATMTDP1L3MBTL1
SCHEMBL20454318 0.89 APP (0.43) GRM4APPATMTDP1L3MBTL1
SCHEMBL3623354 0.88 APP (0.36) GRM4APPATMTDP1L3MBTL1
SCHEMBL574585 0.88 APP (0.44) GRM4APPPTGDR2ATMTDP1
SCHEMBL29379887 0.88 APP (0.44) GRM4APPPTGDR2ATMTDP1
SCHEMBL427566 0.86 APP (0.46) GRM4APPATMTDP1L3MBTL1
SCHEMBL30165319 0.85 APP (0.44) GRM4APPATMTDP1L3MBTL1
SCHEMBL551446 0.85 APP (0.44) GRM4APPATMTDP1L3MBTL1
SCHEMBL4143563 0.80 APP (0.34) GRM4APPATMTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9587173-B2 Chemiluminescent system IMPERIAL TOY LLC (US) 2017-03-07 US claimed
US-20150368555-A1 CHEMILUMINESCENT SYSTEM GREAT ROCK CAPITAL PARTNERS MANAGEMENT, LLC, AS AGENT 2015-12-24 US claimed
US-9109156-B2 Chemiluminescent system IMPERIAL TOY LLC (US) 2015-08-18 US claimed
US-20140166949-A1 Chemiluminescent system GREAT ROCK CAPITAL PARTNERS MANAGEMENT, LLC, AS AGENT 2014-06-19 US claimed
WO-2013102068-A1 CHEMILUMINESCENT SYSTEM MAGGILUME (US) 2013-07-04 WO claimed
US-20130168620-A1 Chemiluminescent system Maggilume, LLC 2013-07-04 US claimed
US-20190070890-A1 DEVICE FOR DISPENSING CHEMILUMINESCENT SOLUTION GREAT ROCK CAPITAL PARTNERS MANAGEMENT, LLC, AS AGENT 2019-03-07 US disclosed
US-10118433-B2 Device for dispensing chemiluminescent solution IMPERIAL TOY LLC (US) 2018-11-06 US disclosed
US-20170087920-A1 DEVICE FOR DISPENSING CHEMILUMINESCENT SOLUTION GREAT ROCK CAPITAL PARTNERS MANAGEMENT, LLC, AS AGENT 2017-03-30 US disclosed
US-9587173-B2 Chemiluminescent system IMPERIAL TOY LLC (US) 2017-03-07 US disclosed
US-20150368555-A1 CHEMILUMINESCENT SYSTEM GREAT ROCK CAPITAL PARTNERS MANAGEMENT, LLC, AS AGENT 2015-12-24 US disclosed
US-9109156-B2 Chemiluminescent system IMPERIAL TOY LLC (US) 2015-08-18 US disclosed
US-20140166949-A1 Chemiluminescent system GREAT ROCK CAPITAL PARTNERS MANAGEMENT, LLC, AS AGENT 2014-06-19 US disclosed
WO-2013102068-A1 CHEMILUMINESCENT SYSTEM MAGGILUME (US) 2013-07-04 WO disclosed
US-20130168620-A1 Chemiluminescent system Maggilume, LLC 2013-07-04 US disclosed