Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.46 |
| ▸ | CNR1 | P21554 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5509595 | 0.85 | CNR2 (0.44) | CNR2CNR1BRD4BAZ2A | |
| SCHEMBL17956189 | 0.83 | SLC6A4 (0.44) | LMNATSHRHTTNPSR1KDM1A | |
| SCHEMBL5659685 | 0.78 | POLB (0.44) | CNR2CNR1LMNATSHRKDM1A | |
| SCHEMBL17956232 | 0.74 | POLB (0.48) | CNR2LMNAKDM1AHPGD | |
| SCHEMBL408279 | 0.73 | GRM2 (0.33) | CNR2CNR1NPSR1 | |
| SCHEMBL7391821 | 0.73 | NPSR1 (0.40) | CNR2CNR1LMNATSHRHTT | |
| SCHEMBL17956197 | 0.72 | ADRA2A (0.53) | TSHRCHRM2CHRM1CHRM3 | |
| SCHEMBL17956247 | 0.71 | CNR2 (0.38) | CNR2CNR1HTTNAMPT | |
| SCHEMBL17956216 | 0.70 | CDK4 (0.37) | CNR2CNR1 | |
| SCHEMBL6236614 | 0.70 | SLC9A1 (0.37) | CNR2CNR1LMNATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833824-A1 | 3-CYCLOALKYLCARBONYL INDOLES AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006069196-A1 | 3-CYCLOALKYLCARBONYL INDOLES AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2006-06-29 | — | — | WO | disclosed |