Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 14/20 | 0.42 |
| ▸ | CA1 | P00915 | 11/20 | 0.42 |
| ▸ | CA9 | Q16790 | 7/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA6 | P23280 | 3/20 | 0.42 |
| ▸ | CA5A | P35218 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8349565 | 0.82 | CA2 (0.54) | CA2CA1CA9CA12CA6 | |
| SCHEMBL11045302 | 0.81 | CA2 (0.45) | CA2CA1CA9CA12CA6 | |
| SCHEMBL301797 | 0.79 | CA2 (0.47) | CA2CA1CA9CA12CA6 | |
| Hydrochloric Acid SCHEMBL12481385 | 0.78 | CA2 (0.45) | CA2CA1CA9CA12CA6 | |
| Hydrochloric Acid SCHEMBL7362559 | 0.78 | CA2 (0.45) | CA2CA1CA9CA12CA6 | |
| SCHEMBL731097 | 0.77 | TAAR1 (0.52) | CA2CA1CA9CA12CA6 | |
| SCHEMBL1807854 | 0.77 | CA2 (0.48) | CA2CA1CA9CA12CA6 | |
| SCHEMBL8355995 | 0.77 | CA2 (0.48) | CA2CA1CA9CA12CA6 | |
| SCHEMBL30096522 | 0.77 | CA2 (0.52) | CA2CA1CA9CA12CA6 | |
| SCHEMBL301742 | 0.77 | CA2 (0.52) | CA2CA1CA9CA12CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549306-A4 | SUBSTITUTED PHENYLSULFONAMIDE INHIBITORS OF BETA AMYLOID PRODUCTION | WYETH CORP (US) | 2007-06-06 | — | — | EP | claimed |
| EP-1549306-A1 | SUBSTITUTED PHENYLSULFONAMIDE INHIBITORS OF BETA AMYLOID PRODUCTION | Wyeth (US) | 2005-07-06 | — | — | EP | claimed |
| WO-2003103660-A1 | SUBSTITUTED PHENYLSULFONAMIDE INHIBITORS OF BETA AMYLOID PRODUCTION | WYETH (US) | 2003-12-18 | — | — | WO | claimed |