SCHEMBL731097

SCHEMBL731097

NCCc1ccccc1S(N)(=O)=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 8/20 0.52
CA1 P00915 7/20 0.48
CA2 P00918 7/20 0.48
CA9 Q16790 5/20 0.48
CA6 P23280 4/20 0.48
CA4 P22748 3/20 0.48
CA12 O43570 3/20 0.48
CA5A P35218 3/20 0.48
CA7 P43166 3/20 0.48
CA5B Q9Y2D0 3/20 0.48
CA14 Q9ULX7 2/20 0.48
CYP2C9 P11712 1/20 0.48
HTR6 P50406 3/20 0.44
HTR2A P28223 2/20 0.44
PTGES2 Q9H7Z7 1/20 0.43
SLC6A2 P23975 1/20 0.42
MPO P05164 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8349565 0.89 CA2 (0.54) CA1CA2CA9CA6CA4
SCHEMBL6671590 0.86 CA1 (0.44) TAAR1CA1CA2CA9CA6
SCHEMBL6680949 0.85 TAAR1 (0.50) TAAR1HTR6HTR2ASLC6A2HTR1D
SCHEMBL1807854 0.83 CA2 (0.48) CA1CA2CA9CA6CA4
SCHEMBL8355995 0.83 CA2 (0.48) CA1CA2CA9CA6CA4
SCHEMBL30469499 0.83 CA2 (0.52) CA1CA2CA9CA6CA4
SCHEMBL1146430 0.83 CA2 (0.52) CA1CA2CA9CA6CA4
SCHEMBL10691220 0.82 CA2 (0.47) CA1CA2CA9CA6CA4
SCHEMBL1805940 0.82 TAAR1 (0.50) TAAR1HTR6HTR2ASLC6A2CYP1A2
SCHEMBL30009738 0.82 TAAR1 (0.52) TAAR1HTR6HTR2ASLC6A2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114235990-A Tuberculosis serum marker screening method and application 宁夏医科大学 2022-03-25 CN claimed
EP-0783366-B1 CHROMATOGRAPHIC RESINS AND METHODS FOR USING SAME UNIV MASSEY (NZ) 2004-08-18 EP claimed
US-5652348-A SOLID SUPPORT MATRIX, IONIZABLE LIGANDS SELECTED RELATIVE TO TARGET COMPOUND MASSEY UNIVERSITY (NZ) 1997-07-29 US claimed
EP-0783366-A1 CHROMATOGRAPHIC RESINS AND METHODS FOR USING SAME MASSEY UNIVERSITY (NZ) 1997-07-16 EP claimed
WO-1996009116-A1 CHROMATOGRAPHIC RESINS AND METHODS FOR USING SAME MASSEY UNIVERSITY (NZ) 1996-03-28 WO claimed
CN-117732437-A Preparation and drug target identification application of switchable sulfhydryl functional magnetic silica nanoparticle 北京青莲百奥生物科技有限公司 2024-03-22 CN disclosed
CN-114235990-A Tuberculosis serum marker screening method and application 宁夏医科大学 2022-03-25 CN disclosed
EP-2823826-A2 Inhibitors of carbonic anhydrase IX Molecular Insight Pharmaceuticals, Inc. (US) 2015-01-14 EP disclosed
US-8877970-B2 Inhibitors of carbonic anhydrase IX MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2014-11-04 US disclosed
EP-2240171-B1 Inhibitors of carbonic anhydrase IX MOLECULAR INSIGHT PHARM INC (US) 2014-08-13 EP disclosed
EP-1718629-B1 Benzopyran compounds useful for the treatment of arrhytmia NISSAN CHEMICAL IND LTD (JP) 2012-12-26 EP disclosed
US-8138209-B2 Substituted picolinamides as MAO-B inhibitors useful for treating obesity JENRIN DISCOVERY, INC. (US) 2012-03-20 US disclosed
WO-2007008963-A1 MAO-B INHIBITORS USEFUL FOR TREATING OBESITY JENRIN DISCOVERY (US) 2007-01-18 WO disclosed
WO-2006137009-A2 FLUORESCENT SULFONAMIDE DERIVATIVES HAVING CARBONIC ANHYDRASE INHIBITING ACTIVITY AND THEIR USE AS THERAPEUTIC AND DIAGNOSTIC AGENTS UNION LIFE SCIENCES LTD (GB) 2006-12-28 WO disclosed
WO-2006137092-A1 FLUORESCENT SULFONAMIDE DERIVATIVES HAVING CARBONIC ANHYDRASE INHIBITING ACTIVITY AND THEIR USE AS THEAPEUTIC AND DIAGNOSTIC AGENTS SUPURAN CLAUDIU T (IT) 2006-12-28 WO disclosed
EP-0783366-B1 CHROMATOGRAPHIC RESINS AND METHODS FOR USING SAME UNIV MASSEY (NZ) 2004-08-18 EP disclosed
US-5945520-A RESIN OF SOLID SUPPORT MATRIX, SPACER ARM AND IONIZABLE FUNCTIONALITY; SPECIFICALLY DESIGNED TO BIND THE TARGET COMPOUND FROM AN AQUEOUS SOLUTION AT BOTH A LOW AND HIGH IONIC STRENGTH MASSEY UNIVERSITY (NZ) 1999-08-31 US disclosed
US-5652348-A SOLID SUPPORT MATRIX, IONIZABLE LIGANDS SELECTED RELATIVE TO TARGET COMPOUND MASSEY UNIVERSITY (NZ) 1997-07-29 US disclosed
EP-0783366-A1 CHROMATOGRAPHIC RESINS AND METHODS FOR USING SAME MASSEY UNIVERSITY (NZ) 1997-07-16 EP disclosed
WO-1996009116-A1 CHROMATOGRAPHIC RESINS AND METHODS FOR USING SAME MASSEY UNIVERSITY (NZ) 1996-03-28 WO disclosed