Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13542998 | 1.00 | TP53 (0.42) | TP53SLC7A5ALDH1A1MAPTPTGS1 | |
| SCHEMBL1604917 | 0.87 | ALDH1A1 (0.39) | TP53SLC7A5ALDH1A1MAPTPTGS1 | |
| SCHEMBL9143730 | 0.82 | ALDH1A1 (0.38) | TP53SLC7A5ALDH1A1MAPTPTGS1 | |
| SCHEMBL14261024 | 0.82 | ALDH1A1 (0.38) | TP53SLC7A5ALDH1A1MAPTPTGS1 | |
| SCHEMBL22355731 | 0.82 | TP53 (0.38) | TP53SLC7A5ALDH1A1MAPTPTGS1 | |
| SCHEMBL607502 | 0.82 | TP53 (0.45) | TP53SLC7A5ALDH1A1MAPTPTGS1 | |
| SCHEMBL607505 | 0.82 | TP53 (0.45) | TP53SLC7A5ALDH1A1MAPTPTGS1 | |
| SCHEMBL17777229 | 0.82 | TP53 (0.38) | TP53SLC7A5ALDH1A1MAPTPTGS1 | |
| SCHEMBL318356 | 0.80 | SLC7A5 (0.48) | TP53SLC7A5ALDH1A1MAPTPTGS1 | |
| SCHEMBL6974551 | 0.80 | SLC7A5 (0.48) | TP53SLC7A5ALDH1A1MAPTPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8178681-B2 | methyl 3-methyl-2-{[2-oxo-1-(2-oxo-ethyl)-1,2,5,6,7,8,9,10-octahydro-cycloocta[b]pyridine-3-carbonyl]-amino}-butyrate; cannabinoid receptor agonist; antiinflammatory agent, immunostimulant, analgesic; atopic dermatitis; excellent in photostability, and have excellent transdermal and oral absorbency | SHIONOGI & CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| WO-2008032164-A2 | BENZIMIDAZOLONE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2008-03-20 | — | — | WO | disclosed |