Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.32 |
| ▸ | GABRP | O00591 | 4/20 | 0.32 |
| ▸ | GABRD | O14764 | 4/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL318356 | 1.00 | SLC7A5 (0.48) | SLC7A5ALDH1A1MAPTPTGS1SLC1A3 | |
| SCHEMBL8966152 | 1.00 | SLC7A5 (0.48) | SLC7A5ALDH1A1MAPTPTGS1SLC1A3 | |
| SCHEMBL5514917 | 0.80 | TP53 (0.42) | SLC7A5ALDH1A1MAPTPTGS1SLC1A3 | |
| SCHEMBL13542998 | 0.80 | TP53 (0.42) | SLC7A5ALDH1A1MAPTPTGS1SLC1A3 | |
| SCHEMBL1604917 | 0.80 | ALDH1A1 (0.39) | SLC7A5ALDH1A1MAPTPTGS1TP53 | |
| SCHEMBL3891579 | 0.79 | SLC7A5 (0.55) | SLC7A5ALDH1A1MAPTPTGS1SLC1A3 | |
| SCHEMBL4441664 | 0.79 | SLC7A5 (0.55) | SLC7A5ALDH1A1MAPTPTGS1SLC1A3 | |
| Methane SCHEMBL2033946 | 0.77 | SLC7A5 (0.52) | SLC7A5ALDH1A1MAPTPTGS1SLC1A3 | |
| SCHEMBL11536438 | 0.77 | SLC7A5 (0.40) | SLC7A5ALDH1A1MAPTPTGS1SLC1A3 | |
| SCHEMBL12563243 | 0.77 | SLC7A5 (0.40) | SLC7A5ALDH1A1MAPTPTGS1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869786-B1 | PHARMACEUTICAL COMPOUNDS | LILLY CO ELI (US) | 2003-03-05 | — | — | EP | disclosed |