Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ABAT | P80404 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15204255 | 0.81 | TSHR (0.49) | TSHRCDC25AKDM4EMAPTPOLB | |
| SCHEMBL11741569 | 0.79 | — | — | |
| SCHEMBL5517614 | 0.78 | CDC25A (0.47) | TSHRCDC25AGAA | |
| SCHEMBL5513167 | 0.77 | TSHR (0.37) | TSHRNAPRTKDM4EGAAMAPT | |
| SCHEMBL5521559 | 0.77 | CDC25A (0.47) | TSHRCDC25AMAPT | |
| SCHEMBL3081010 | 0.72 | — | — | |
| SCHEMBL5806703 | 0.70 | — | — | |
| SCHEMBL29994134 | 0.70 | RAB9A (0.39) | TSHRNAPRTKDM4EGAAMAPT | |
| SCHEMBL4581202 | 0.70 | — | — | |
| SCHEMBL7260351 | 0.69 | IDO1 (0.46) | KDM4EMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470258-B1 | COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS | TFL LEDERTECHNIK GMBH (DE) | 2013-08-28 | — | — | EP | disclosed |
| US-7250456-B2 | Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials | TFL LEDERTECHNIK GMBH (DE) | 2007-07-31 | — | — | US | disclosed |
| US-20050148702-A1 | Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials | TFL LEDERTECHNIK GMBH (DE) | 2005-07-07 | — | — | US | disclosed |
| EP-1470258-A1 | COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS | TFL Ledertechnik GmbH (DE) | 2004-10-27 | — | — | EP | disclosed |
| EP-1165509-B1 | METHOD OF PRODUCING 3,4-DIHYDROPROLINES AND 3,4-DEHYDROPIPERIDINES | ABBOTT GMBH & CO KG (DE) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003064707-A1 | COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS | TFL LEDERTECHNIK GMBH (DE) | 2003-08-07 | — | — | WO | disclosed |
| US-6579971-B1 | Derivatives by reacting with a strong base and compound of given formula; hydrolysis; useful intermediates for the synthesis of dyes, pesticides or drugs (thrombin inhibitors) | BASF AKTIENGESELLSCHAFT (DE) | 2003-06-17 | — | — | US | disclosed |
| EP-1165509-A1 | METHOD OF PRODUCING 3,4-DIHYDROPROLINES AND 3,4-DEHYDROPIPERIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000058284-A1 | METHOD OF PRODUCING 3,4-DIHYDROPROLINES AND 3,4-DEHYDROPIPERIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-05 | — | — | WO | disclosed |
| US-4243672-A | CARDIOVASCULAR DISORDERS; CARDIOTONIC AGENTS | PFIZER INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4243672-A | CARDIOVASCULAR DISORDERS; CARDIOTONIC AGENTS | PFIZER INC. (US) | 1981-01-06 | — | — | US | disclosed |
| EP-0009326-A2 | Pyrrolyl keto and amino acids and derivatives thereof, processes for their preparation and pharmaceutical compositions containing them | Pfizer Limited (GB) | 1980-04-02 | — | — | EP | disclosed |