Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FABP1 | P07148 | 1/20 | 0.41 |
| ▸ | FABP6 | P51161 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14980560 | 0.84 | KDM4E (0.46) | HSD17B10KMT2AMEN1MAPTKDM4E | |
| SCHEMBL11741569 | 0.71 | — | — | |
| SCHEMBL5806703 | 0.71 | — | — | |
| SCHEMBL4581202 | 0.71 | — | — | |
| SCHEMBL6266880 | 0.70 | — | — | |
| SCHEMBL28858799 | 0.70 | — | — | |
| SCHEMBL5394291 | 0.69 | CYP19A1 (0.52) | HTTHSD17B10KMT2AMEN1KDM4E | |
| SCHEMBL28677353 | 0.69 | MEN1 (0.50) | IDO1THRBKMT2AMEN1TDP1 | |
| SCHEMBL5514932 | 0.69 | PARP1 (0.45) | MAPTKDM4EPOLB | |
| SCHEMBL10404614 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003068738-A1 | PYRROLE DERIVATIVES AS LIGANDS OF MELANOCORTIN RECEPTORS | NEUROCRINE BIOSCIENCES, INC. (US) | 2003-08-21 | — | — | WO | disclosed |