Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 6/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CALML3 | P27482 | 1/20 | 0.33 |
| ▸ | SDHA | P31040 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5999673 | 0.84 | MAOA (0.52) | MAOAMAOBOPRM1OPRK1OPRL1 | |
| SCHEMBL5503079 | 0.83 | MAOA (0.39) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL5998076 | 0.83 | MAOA (0.39) | MAOAMAOBOPRM1OPRK1OPRL1 | |
| SCHEMBL5536716 | 0.81 | MAOA (0.50) | MAOAMAOBOPRM1OPRK1OPRL1 | |
| SCHEMBL5998696 | 0.81 | MAOA (0.50) | MAOAMAOBOPRM1OPRK1OPRL1 | |
| SCHEMBL5999433 | 0.79 | MAOA (0.38) | MAOAMAOBOPRM1OPRK1OPRL1 | |
| SCHEMBL5998591 | 0.79 | MAOA (0.38) | MAOAMAOBOPRM1OPRK1OPRL1 | |
| SCHEMBL5999423 | 0.79 | MAOA (0.38) | MAOAMAOBOPRM1OPRK1OPRL1 | |
| SCHEMBL5114634 | 0.77 | MAOB (0.48) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL5114642 | 0.77 | MAOB (0.48) | MAOAMAOBLMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781642-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006016221-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-16 | — | — | WO | disclosed |