SCHEMBL5515518

SCHEMBL5515518

O=C(O)CCOn1cccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.44
LMNA P02545 5/20 0.36
ALKBH5 Q6P6C2 1/20 0.35
SUCNR1 Q9BXA5 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
KEAP1 Q14145 1/20 0.32
SLC22A6 Q4U2R8 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
MCL1 Q07820 1/20 0.32
ALDH1A1 P00352 2/20 0.31
EGLN3 Q9H6Z9 1/20 0.31
NR4A2 P43354 1/20 0.31
TSHR P16473 1/20 0.31
NFKB1 P19838 1/20 0.31
PMP22 Q01453 1/20 0.31
FFAR1 O14842 1/20 0.31
NSD2 O96028 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5509639 0.87 TDP1 (0.54) TDP1LMNASLC22A6KMT2AALDH1A1
SCHEMBL5512357 0.85 TDP1 (0.62) TDP1LMNASLC22A6ALDH1A1TSHR
SCHEMBL5511530 0.76 TSHR (0.42) TDP1L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL29135022 0.74 TDP1 (0.78) TDP1ALDH1A1EGLN3
Benzene SCHEMBL28250568 0.69 LMNA (0.47) LMNAALKBH5SUCNR1EGLN1L3MBTL1
SCHEMBL28173247 0.68 TSHR (0.47) TDP1LMNASLC22A6KMT2ATSHR
Benzene SCHEMBL27391276 0.65 ALDH1A1 (0.58) LMNAALKBH5SUCNR1EGLN1L3MBTL1
Succinic Acid SCHEMBL4739951 0.64 LMNA (0.82) TDP1LMNAALKBH5SUCNR1EGLN1
SCHEMBL524907 0.64 EGLN3 (0.54) LMNAALKBH5SUCNR1EGLN1MEN1
SCHEMBL375634 0.63 LMNA (0.53) TDP1LMNAALKBH5SUCNR1EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470258-B1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2013-08-28 EP disclosed
US-7250456-B2 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2007-07-31 US disclosed
US-20050148702-A1 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2005-07-07 US disclosed
EP-1470258-A1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL Ledertechnik GmbH (DE) 2004-10-27 EP disclosed
WO-2003064707-A1 COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2003-08-07 WO disclosed