Hydrochloric Acid

Hydrochloric Acid

SCHEMBL5516481

CC1=Cc2ccccc2C1[Zr+2]1(C2C(C)=Cc3ccccc32)CC1C.[Cl-].[Cl-]

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.34
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34
DRD2 P14416 1/20 0.31
DRD4 P21917 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7663823 0.87 CYP19A1 (0.33) CYP19A1CYP11B1CYP11B2DRD2DRD4
Hydrochloric Acid SCHEMBL4077625 0.81 CYP11B1 (0.35) CYP11B1CYP11B2
Hydrochloric Acid SCHEMBL5512075 0.79 CYP19A1 (0.33) CYP19A1CYP11B1CYP11B2
Hydrochloric Acid SCHEMBL649477 0.79 CYP11B1 (0.33) CYP19A1CYP11B1CYP11B2
Hydrochloric Acid SCHEMBL10711045 0.79 CYP11B1 (0.33) CYP19A1CYP11B1CYP11B2
Hydrochloric Acid SCHEMBL338766 0.79 CYP11B1 (0.33) CYP19A1CYP11B1CYP11B2
Hydrochloric Acid SCHEMBL5351284 0.76 CYP19A1 (0.31) CYP19A1CYP11B1CYP11B2
Hydrochloric Acid SCHEMBL8630637 0.76 CYP11B1 (0.32) CYP19A1CYP11B1CYP11B2
Hydrochloric Acid SCHEMBL5515666 0.76 CYP19A1 (0.31) CYP19A1CYP11B1CYP11B2
Fluoride Ion SCHEMBL1130323 0.75 HTR2C (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7208559-B2 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2007-04-24 US disclosed
US-20060135712-A1 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2006-06-22 US disclosed
EP-0930329-B1 SHRINKABLE FILM MADE FROM OLEFIN COPOLYMER MITSUI CHEMICALS INC (JP) 2004-09-22 EP disclosed
US-6300416-B1 USEFUL AS TIRE SIDEWALL OR TIRE TREAD; STRENGTH PROPERTIES AND BENDING FATIGUE RESISTANCE AND LOW FUEL CONSUMPTION MITSUI CHEMICALS, INC. (JP) 2001-10-09 US disclosed
US-6194501-B1 ALPHA-OLEFIN-VINYLAROMATIC COPOLYMER AND TACKIFIER RESINS MITSUI CHEMICALS INC (JP) 2001-02-27 US disclosed
US-6015625-A COMPOSITION CONTAINING ALPHA-OLEFIN/AROMATIC VINYL COMPOUND RANDOM COPOLYMER GRAFT MODIFIED WITH UNSATURATED CARBOXYLIC ACID OR DERIVATIVE MITSUI CHEMICALS, INC. (JP) 2000-01-18 US disclosed
EP-0930329-A1 SHRINKABLE FILM MADE FROM OLEFIN COPOLYMER Mitsui Chemicals, Inc. (JP) 1999-07-21 EP disclosed
EP-0896044-A1 ADHESIVE RESIN COMPOSITION AND LAMINATE MADE USING THE SAME AS ADHESIVE LAYER Mitsui Chemicals, Inc. (JP) 1999-02-10 EP disclosed
EP-0893245-A1 VULCANIZED MOLDING HAVING SURFACE DECORATIVE LAYER, PAINTED THERMOPLASTIC RESIN COMPOSITION, AND PAINTED ELASTOMER COMPOSITION Mitsui Chemicals, Inc. (JP) 1999-01-27 EP disclosed
EP-0889091-A1 RUBBER COMPOSITIONS FOR TIRES Mitsui Chemicals, Inc. (JP) 1999-01-07 EP disclosed