Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10711045 | 1.00 | CYP11B1 (0.33) | CYP11B1CYP11B2CYP19A1HTR2C | |
| Hydrochloric Acid SCHEMBL338766 | 1.00 | CYP11B1 (0.33) | CYP11B1CYP11B2CYP19A1HTR2C | |
| Fluoride Ion SCHEMBL1130323 | 0.96 | HTR2C (0.31) | HTR2C | |
| Hydrochloric Acid SCHEMBL5515666 | 0.93 | CYP19A1 (0.31) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL5351284 | 0.93 | CYP19A1 (0.31) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL6433415 | 0.92 | DRD2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL8095200 | 0.88 | CYP11B1 (0.31) | CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL438570 | 0.85 | — | — | |
| Syringol SCHEMBL7938369 | 0.81 | HTR2C (0.35) | CYP19A1HTR2C | |
| Hydrochloric Acid SCHEMBL7196668 | 0.81 | ALDH1A1 (0.33) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1852408-B1 | PROCESS FOR THE DIMERIZATION OF ALPHA-OLEFINS | IDEMITSU KOSAN CO (JP) | 2018-04-04 | — | — | EP | disclosed |
| US-20130225892-A1 | PROCESS FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2013-08-29 | — | — | US | disclosed |
| US-20120088946-A1 | PROCESS FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2012-04-12 | — | — | US | disclosed |
| US-8119850-B2 | Process for producing unsaturated hydrocarbon compound | IDEMITSU KOSAN CO., LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-20090069614-A1 | METHOD FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2009-03-12 | — | — | US | disclosed |
| US-20090030255-A1 | PROCESS FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2009-01-29 | — | — | US | disclosed |
| EP-1852408-A1 | PROCESS FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2007-11-07 | — | — | EP | disclosed |
| EP-1849757-A1 | METHOD FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2007-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030255-A1 | PROCESS FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND | ALOX12, ALOX15B, ALOX15 | CYP11B1 159/4885CYP11B2 183/4885CYP19A1 82/4885 |
| US-20090069614-A1 | METHOD FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND | AHR, ALOX12, ARNT | CYP11B1 465/4885CYP11B2 559/4885CYP19A1 66/4885 |
| US-20120088946-A1 | PROCESS FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND | ALOX12, ALOX15B, ALOX15 | CYP11B1 159/4885CYP11B2 183/4885CYP19A1 82/4885 |
| US-20130225892-A1 | PROCESS FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND | ALOX12, ALOX15B, ALOX15 | CYP11B1 159/4885CYP11B2 183/4885CYP19A1 82/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.