Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL73835 | 0.94 | KMT2A (0.43) | HRH2HRH1FAAHKMT2AMEN1 | |
| SCHEMBL73832 | 0.88 | KMT2A (0.43) | HRH2HRH1FAAHKMT2AMEN1 | |
| SCHEMBL73236 | 0.86 | MAPT (0.43) | FAAHKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL72465 | 0.75 | PTGDR2 (0.45) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8301729 | 0.72 | MGLL (0.64) | HRH2HRH1MGLLFAAHKMT2A | |
| SCHEMBL72705 | 0.69 | PTGDR2 (0.42) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7050093 | 0.69 | PDE4A (0.48) | KMT2ASMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL73099 | 0.69 | PTGDR2 (0.44) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL75121 | 0.68 | MAPT (0.45) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL73073 | 0.67 | ADORA1 (0.42) | MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831227-A2 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS | Glenmark Pharmaceuticals S.A. (CH) | 2007-09-12 | — | — | EP | claimed |
| WO-2006064355-A2 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS | GLENMARK PHARMACEUTICALS S.A. (US) | 2006-06-22 | — | — | WO | claimed |