Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1582331 | 0.91 | EGFR (0.32) | EGFR | |
| SCHEMBL5517030 | 0.90 | DPP4 (0.32) | LMNAMEN1HPGDKMT2AALDH1A1 | |
| SCHEMBL5531085 | 0.90 | EGFR (0.31) | EGFR | |
| SCHEMBL5525474 | 0.88 | PTPN1 (0.34) | DPP4DPP8DPP9EGFR | |
| SCHEMBL5528276 | 0.85 | BID (0.35) | ALDH1A1 | |
| SCHEMBL5525472 | 0.85 | LDHA (0.32) | DPP4DPP8DPP9EGFR | |
| SCHEMBL5531082 | 0.84 | EGFR (0.33) | MEN1HPGDKMT2AALDH1A1EGFR | |
| SCHEMBL5512213 | 0.83 | KDM4E (0.31) | ALDH1A1 | |
| SCHEMBL5528272 | 0.83 | GABRP (0.35) | ALDH1A1DPP4RARB | |
| SCHEMBL5526605 | 0.82 | ACE2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7282601-B2 | Dicarboxylic diester, process for producing the same, and refrigerating machine lubricating oil comprising the ester | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2007-10-16 | — | — | US | disclosed |
| US-7271282-B1 | Dicarboxylic diester, process for producing the same, and refrigerating machine lubricating oil comprising the ester | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2007-09-18 | — | — | US | disclosed |