Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LIPE | Q05469 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5517038 | 1.00 | NAMPT (0.50) | NAMPTMAPTL3MBTL1ALDH1A1PTPN1 | |
| SCHEMBL11586577 | 0.79 | MAPK1 (0.51) | MAPTL3MBTL1ALDH1A1LMNATSHR | |
| SCHEMBL11586576 | 0.79 | MAPK1 (0.51) | MAPTL3MBTL1ALDH1A1LMNATSHR | |
| SCHEMBL2249223 | 0.79 | ALDH1A1 (0.53) | MAPTL3MBTL1ALDH1A1PTPN1LMNA | |
| SCHEMBL2249228 | 0.79 | ALDH1A1 (0.53) | MAPTL3MBTL1ALDH1A1PTPN1LMNA | |
| Hydrochloric Acid SCHEMBL11586138 | 0.78 | MAPK1 (0.50) | L3MBTL1ALDH1A1LMNATSHRKDM4E | |
| Hydrochloric Acid SCHEMBL11586141 | 0.78 | MAPK1 (0.50) | L3MBTL1ALDH1A1LMNATSHRKDM4E | |
| SCHEMBL11588121 | 0.77 | ALDH1A1 (0.47) | MAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL11588118 | 0.77 | ALDH1A1 (0.47) | MAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL11584483 | 0.77 | LTA4H (0.46) | ALDH1A1LMNASMN1; SMN2USP2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7282608-B2 | Inhibitors of histone deacetylase | METHYLGENE, INC. (CA) | 2007-10-16 | — | — | US | disclosed |
| US-20060020131-A1 | Aryl amide, -sulfonamide, or -urea derivatives; antiproliferative, antitumor, anticarcinogenic, and/or antimetastasis agents | METHYLGENE, INC. (CA) | 2006-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060020131-A1 | Aryl amide, -sulfonamide, or -urea derivatives; antiproliferative, antitumor, anticarcinogenic, and/or antimetastasis agents | HDAC1, AADAC, HDAC11 | NAMPT 351/4885MAPT 2938/4885L3MBTL1 3034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.